Quetiapine impurity 64 CAS 73486-81-4

Purity 97%+In StockPharmacopoeial Impurity Standards
CAS No.73486-81-4
Molecular FormulaC8H17N3O3
Molecular Weight203.24 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Quetiapine impurity 64 CAS 73486-81-4 chemical structure

Description

As a certified reference material (CRM), Quetiapine impurity 64 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

As a process- or degradation-related impurity, Quetiapine impurity 64 (CAS 73486-81-4, C8H17N3O3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.

Quetiapine impurity 64 (C8H17N3O3) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.

Physical & Chemical Properties

Molecular FormulaC8H17N3O3
Molecular Weight203.24 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in methanol, ethanol, DMSO
StabilityLight-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)2.0
CAS Registry Year (est.)1977
Nitrogen Atoms3

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