3-(p-Tolyl)isoxazol-5(4H)-one CAS 25755-82-2
| CAS No. | 25755-82-2 |
| Molecular Formula | C10H9NO2 |
| Molecular Weight | 175.18 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 3-(p-Tolyl)isoxazol-5(4H)-one is closely related to an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
3-(p-Tolyl)isoxazol-5(4H)-one (CAS 25755-82-2) is a high-purity analytical reference standard with the molecular formula C10H9NO2 and a molecular weight of 175.18 g/mol.
The molecular framework of 3-(p-Tolyl)isoxazol-5(4H)-one (C10H9NO2) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H9NO2 |
| Molecular Weight | 175.18 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1964 |
| Nitrogen Atoms | 1 |
Related p Standards
- 2-(P-tolyl)oxazol-5(4H)-one (CAS 75152-18-0)
- 5-(p-Tolyl)isoxazol-3-ol (CAS 21053-25-8)
- 5-(M-tolyl)-1,2,4-oxadiazol-3-amine (CAS 1017521-44-6)
- 5-(O-tolyl)-1,2,4-oxadiazol-3-amine (CAS 1017521-47-9)
- 5-(m-tolyl)-1,3,4-oxadiazol-2-amine (CAS 109060-64-2)
- 5-(O-tolyl)-1,3,4-oxadiazol-2-amine (CAS 1750-78-3)
- 3-(p-Tolyl)-1H-1,2,4-triazol-5(4H)-one (CAS 3214-02-6)
- 5-(P-tolyl)-1,2,4-oxadiazol-3-amine (CAS 23275-54-9)
Recommended Standards
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- (2-((4-Fluorobenzyl)thio)-1-methyl-1H-imidazol-5-yl)methanol (CAS 338422-40-5)
- (2R)-3-Methyl-2-(piperazin-2-yl)butan-2-ol (CAS 1321925-09-0)
- Umeclidinium Impurity 10 (CAS 461648-39-5)
- 2,6-Difluoro-3-(phenylmethoxy)benzaldehyde (CAS 152434-87-2)
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