2-(P-tolyl)oxazol-5(4H)-one CAS 75152-18-0
| CAS No. | 75152-18-0 |
| Molecular Formula | C10H9NO2 |
| Molecular Weight | 175.18 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-(P-tolyl)oxazol-5(4H)-one.
2-(P-tolyl)oxazol-5(4H)-one (CAS 75152-18-0) is a high-purity analytical reference standard with the molecular formula C10H9NO2 and a molecular weight of 175.18 g/mol.
Structurally, 2-(P-tolyl)oxazol-5(4H)-one (C10H9NO2) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 7.0, corresponding to approximately 7 ring(s) or double-bond equivalent(s). With a molecular weight of 175.18 g/mol, it falls into the medium-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-(P-tolyl)oxazol-5(4H)-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H9NO2 |
| Molecular Weight | 175.18 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1978 |
| Nitrogen Atoms | 1 |
Related P Standards
- 3-(p-Tolyl)isoxazol-5(4H)-one (CAS 25755-82-2)
- 5-(p-Tolyl)isoxazol-3-ol (CAS 21053-25-8)
- 5-(M-tolyl)-1,2,4-oxadiazol-3-amine (CAS 1017521-44-6)
- 5-(O-tolyl)-1,2,4-oxadiazol-3-amine (CAS 1017521-47-9)
- 5-(m-tolyl)-1,3,4-oxadiazol-2-amine (CAS 109060-64-2)
- 5-(O-tolyl)-1,3,4-oxadiazol-2-amine (CAS 1750-78-3)
- 3-(p-Tolyl)-1H-1,2,4-triazol-5(4H)-one (CAS 3214-02-6)
- 5-(P-tolyl)-1,2,4-oxadiazol-3-amine (CAS 23275-54-9)
Recommended Standards
- 2-(Prop-2-yn-1-yloxy)benzamide (CAS 66362-34-3)
- 2,4-Dimethylisoindoline-1,3-dione (CAS 83844-42-2)
- 2-(Prop-2-yn-1-yloxy)benzaldehyde oxime (CAS 55241-70-8)
- 2,6-Dimethyl-4H-benzo[d][1,3]oxazin-4-one (CAS 62175-49-9)
- 2-(4-(3,3-Difluorocyclobutyl)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 2361225-63-8)
- 6-Bromo-1,3-dimethyl-2-oxo-2,3-dihydro-1h-1,3-benzodiazole-5-sulfonamide (CAS 1354950-91-6)
- Methyl 3-amino-3-(2-chloro-5-methylphenyl)propanoate (CAS 1824657-51-3)
- 2-bromo-1-(bromomethyl)-3-methylbenzene (CAS 66790-58-7)
- 2,6-Dimethylnaphthalene-d12 (CAS 350820-12-1)
- Rizatriptan - API Standards (CAS 144034-80-0)
- 1-[5-(difluoromethyl)-1,2,4-oxadiazol-3-yl]ethan-1-amine hydrochloride (CAS 1423023-87-3)
- Fluorescein Impurity 10 (CAS CATO-C4X-290010)
- 3-Nitro-2-((tetrahydro-2H-pyran-4-yl)methoxy)pyridine (CAS 1287218-02-3)
- Semaglutide Impurity 147 (CAS CATO-C4X-2226147)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com