3,6,8-Trichloroquinolin-4-ol CAS 25771-92-0
| CAS No. | 25771-92-0 |
| Molecular Formula | C9H4Cl3NO |
| Molecular Weight | 248.49 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 3,6,8-Trichloroquinolin-4-ol (C9H4Cl3NO) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
3,6,8-Trichloroquinolin-4-ol (CAS 25771-92-0), molecular formula C9H4Cl3NO and molecular weight 248.49 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 3,6,8-Trichloroquinolin-4-ol under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C9H4Cl3NO |
| Molecular Weight | 248.49 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1964 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Trichloroquinolin Standards
- 2,5,7-Trichloroquinolin-8-ol (CAS 101870-58-0)
- 3,5,7-Trichloroquinolin-4(1H)-one (CAS 1204811-23-3)
- 3,6,8-Trichloroquinolin-2(1H)-one (CAS 1708079-73-5)
- 4,7,8-Trichloroquinolin-2(1H)-one (CAS 2322832-98-2)
- 5,6,7-Trichloroquinolin-8-ol (CAS 5541-71-9)
- 5,7,7-trichloroquinolin-8(7H)-one 687638-05-7 (CAS 687638-05-7)
- 2,4,8-Trichloroquinolin-3-amine (CAS 1447959-14-9)
- 5,7,8-Trichloroquinolin-6-ol (CAS 5423-56-3)
Recommended Standards
- 2-Methyl-N-(2,2,2-trichloroacetyl)alanine (CAS 95038-13-4)
- 3-Ethoxy-5-(trichloromethyl)-4,5-dihydroisoxazol-5-ol (CAS 639815-70-6)
- 2,5,6-Trichloro-1H-indole-3-carbaldehyde (CAS 800400-47-9)
- 4,6-Dichloro-1H-indole-2-carbonyl chloride (CAS 306937-25-7)
- 3-(2-(Dimethylamino)vinyl)-5,5-dimethylcyclohex-2-en-1-one (CAS 128475-82-1)
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- N-(trifluoroacetyl)-Alanyl Chloride (CAS 1597-19-9)
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- 1-(Perfluorophenyl)propan-1-ol (CAS 25622-74-6)
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