(4-Benzoylpiperidin-1-yl)(3-(2,6-dichlorophenyl)-5-methylisoxazol-4-yl)methanone CAS 257946-66-0
| CAS No. | 257946-66-0 |
| Molecular Formula | C23H20Cl2N2O3 |
| Molecular Weight | 443.32 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of (4-Benzoylpiperidin-1-yl)(3-(2,6-dichlorophenyl)-5-methylisoxazol-4-yl)methanone is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies (4-Benzoylpiperidin-1-yl)(3-(2,6-dichlorophenyl)-5-methylisoxazol-4-yl)methanone (CAS 257946-66-0), a certified reference material (molecular formula C23H20Cl2N2O3, MW 443.32 g/mol) for analytical method development and quality control.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, (4-Benzoylpiperidin-1-yl)(3-(2,6-dichlorophenyl)-5-methylisoxazol-4-yl)methanone is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 443.32 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C23H20Cl2N2O3 |
| Molecular Weight | 443.32 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Benzoylpiperidin Standards
- N-((1-Benzoylpiperidin-4-yl)methyl)-4-fluorobenzamide (CAS 1956324-58-5)
- 5-(1-Benzoylpiperidin-4-yl)-1,3,4-thiadiazol-2-amine (CAS 1199215-65-0)
- 1-(4-Benzoylpiperidin-1-yl)-2,2,2-trifluoroethan-1-one (CAS 257946-67-1)
- 3-(1-Benzoylpiperidin-2-yl)pyridin-2(1H)-one (CAS 1352500-58-3)
- 5-(1-Benzoylpiperidin-4-yl)-1,3,4-oxadiazol-2-ol (CAS 1417362-98-1)
- 3-(1-Benzoylpiperidin-4-yl)propanoic acid (CAS 75999-93-8)
- Methyl 2-(1-benzoylpiperidin-4-yl)acetate (CAS 80221-38-1)
- 2-(1-Benzoylpiperidin-4-yl)acetic acid (CAS 56772-11-3)
Recommended Standards
- 3,3'-Dichloro-2,2'-bis(methoxymethoxy)-(+-)-1,1'-binaphthalene (CAS 142010-86-4)
- 1-(3-Chloro-1,4-dioxo-1,4-dihydronaphthalen-2-yl)-N-(3-chlorobenzyl)piperidine-4-carboxamide (CAS 439108-55-1)
- KPT-330 (CAS 1421923-86-5)
- 1-Benzyl-2-((4-bromobenzyl)thio)-5,6-dihydro-1H-imidazo[4,5-d]pyridazine-4,7-dione (CAS 3434-16-0)
- Biphenyl-d10 (CAS 1486-01-7)
- 1-(1H-Pyrazolo[3,4-c]pyridin-3-yl)ethan-1-one (CAS 1386462-22-1)
- Ethyl 2-(benzo[b]thiophen-3-yl)acetate (CAS 7597-68-4)
- 3-Methoxy-N-(2-(3-(piperazin-1-ylmethyl)imidazo[2,1-b]thiazol-6-yl)phenyl)benzamide (CAS 925437-59-8)
- Leucogen (CAS 1950-36-3)
- 3-(2-Chloroacetamido)-4-methylbenzoic acid (CAS 731011-85-1)
- (S)-4-(1-Aminopropyl)phenol hydrochloride (CAS 2368884-26-6)
- Naltrexone impurity 37 (CAS CATO-C4X-147537)
- 2-(4-Acetyl-5,5-dimethyl-4,5-dihydro-1,3,4-oxadiazol-2-yl)acetonitrile (CAS 130781-62-3)
- Exenatide (CAS 141758-74-9（free base）)
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