2-[(3-Chlorobenzyl)thio]-4,5-dihydro-1H-imidazole hydrochloride CAS 258347-64-7
| CAS No. | 258347-64-7 |
| Molecular Formula | C10H11ClN2S |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 263.18 g/mol gives 2-[(3-Chlorobenzyl)thio]-4,5-dihydro-1H-imidazole hydrochloride distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
2-[(3-Chlorobenzyl)thio]-4,5-dihydro-1H-imidazole hydrochloride (CAS 258347-64-7), molecular formula C10H11ClN2SHCl and molecular weight 263.18 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2-[(3-Chlorobenzyl)thio]-4,5-dihydro-1H-imidazole hydrochloride (C10H11ClN2SHCl) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H11ClN2S HCl |
| Molecular Weight | 263.18 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Chlorobenzyl Standards
- 1-(4-Chlorobenzyl)-5-methyl-3-nitro-1h-pyrazole (CAS 1001510-38-8)
- 1-(3-Chlorobenzyl)-5-methyl-3-nitro-1h-pyrazole (CAS 1001566-82-0)
- 1-(3-Chlorobenzyl)-1H-pyrazol-4-amine (CAS 1002033-41-1)
- 3-(2-Chlorobenzyl)pyrrolidine (CAS 1003561-98-5)
- 1-(3-Chlorobenzyl)-4-isothiocyanato-1h-pyrazole (CAS 1004193-35-4)
- 1-(3-Chlorobenzyl)-5-methyl-1,2-dihydro-3h-pyrazol-3-imine (CAS 1004643-48-4)
- 1-(4-Chlorobenzyl)-2-oxo-N-(3-phenylpropyl)-1,2-dihydro-1,8-naphthyridine-3-carboxamide (CAS 1005291-55-3)
- 1-(2-Chlorobenzyl)-5-methyl-3,4-dinitro-1h-pyrazole (CAS 1005669-24-8)
Recommended Standards
- (R)-1-((Benzyloxy)carbonyl)azepane-3-carboxylic acid (CAS 1419222-29-9)
- 4-({[(4-hydroxyphenyl)methyl](methyl)amino}methyl)phenol (CAS 89803-09-8)
- 1-(3,4-Dihydro-2H-pyrrol-5-yl)-1-(4-methoxyphenyl)-3-(o-tolyl)urea (CAS 898444-04-7)
- 3-Diphenylacetylaminopropionic acid (CAS 65707-89-3)
- 4-Bromo-6-chloro-1H-pyrrolo[2,3-b]pyridine (CAS 942920-50-5)
- Resmetirom impurity 64 (CAS 2375196-15-7)
- 1-{[4-(hydroxymethyl)phenyl]sulfanyl}-N,N-dimethylformamide (CAS 1461704-91-5)
- 2-[(3,3,3-trifluoropropyl)amino]acetonitrile (CAS 1341612-55-2)
- 2-Methylhexane (CAS 591-76-4)
- Semaglutide impurity 259 (CAS CATO-C4X-2226259)
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