Resmetirom impurity 64 CAS 2375196-15-7
| CAS No. | 2375196-15-7 |
| Molecular Formula | C7H9ClN2O |
| Molecular Weight | 172.61 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Resmetirom impurity 64 (CAS 2375196-15-7) is a certified pharmaceutical impurity reference standard with the molecular formula C7H9ClN2O and a molecular weight of 172.61 g/mol.
Owing to an amide group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system, Resmetirom impurity 64 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 172.61 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO manufactures Resmetirom impurity 64 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C7H9ClN2O |
| Molecular Weight | 172.61 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1999 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Resmetirom Standards
- Resmetirom impurity 65 (CAS 1696366-11-6)
- Resmetirom impurity 134 (CAS 28165-63-1)
- Resmetirom impurity 133 (CAS 1314924-95-2)
- Resmetirom impurity 135 (CAS 3096249-74-7)
- Resmetirom Impurity 3 (CAS 6629-04-5)
- Resmetirom Impurity 44 (CAS CATO-C4X-291244)
- Resmetirom Impurity 4 (CAS 107228-51-3)
- Resmetirom Impurity 45 (CAS CATO-C4X-291245)
Recommended Standards
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- 6-(Aminomethyl)-5-cyclopropoxynicotinonitrile (CAS 1243479-85-7)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com