2-(1,3-Dioxoisoindolin-2-yl)-N-phenylethane-1-sulfonamide CAS 25840-58-8
| CAS No. | 25840-58-8 |
| Molecular Formula | C16H14N2O4S |
| Molecular Weight | 330.36 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 2-(1,3-Dioxoisoindolin-2-yl)-N-phenylethane-1-sulfonamide (C16H14N2O4S) is characterized by a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
2-(1,3-Dioxoisoindolin-2-yl)-N-phenylethane-1-sulfonamide (CAS 25840-58-8) is a high-purity analytical reference standard with the molecular formula C16H14N2O4S and a molecular weight of 330.36 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C16H14N2O4S |
| Molecular Weight | 330.36 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1964 |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Dioxoisoindolin Standards
- 1,3-Dioxoisoindolin-2-yl 2-formylbenzenesulfonate (CAS 199432-74-1)
- 4-[(1,3-dioxoisoindolin-2-yl)methyl]cyclohexanesulfonic acid (CAS 2402803-17-0)
- 2-(1,3-Dioxoisoindolin-2-yl)ethyl benzenesulfonate (CAS 13031-58-8)
- 11-(1,3-Dioxoisoindolin-2-yl)undecanoic acid (CAS 4403-42-3)
- 4-(3-(1,3-Dioxoisoindolin-2-yl)propyl)-3-methyl-5-oxo-2,5-dihydro-1H-pyrazole-1-carboximidamide (CAS 866145-62-2)
- N-(1,3-Dioxoisoindolin-4-yl)-2-(ethylthio)benzamide (CAS 922689-94-9)
- N-(1,3-Dioxoisoindolin-4-yl)-3,5-dimethoxybenzamide (CAS 406917-05-3)
- (1,3-Dioxoisoindolin-2-yl)methyl 2-bromo-2-methylpropanoate (CAS 903562-13-0)
Recommended Standards
- 1-Benzyl-4-(4-fluorophenoxy)phthalazine (CAS 338404-25-4)
- 2-(3-(((Benzyloxy)carbonyl)amino)propanamido)ethane-1-sulfonic acid (CAS 53329-43-4)
- (E)-2-(4-((4-nitrobenzyl)oxy)benzylidene)hydrazine-1-carbothioamide (CAS 402600-59-3)
- 2-(4-Methoxyphenyl)-5-(2-(methylsulfonyl)phenyl)-1,3,4-oxadiazole (CAS 339014-36-7)
- Tert-butyl (2,5-dioxotetrahydrofuran-3-yl)carbamate (CAS 120409-48-5)
- 2,3-Dichloro-5-mercaptopyridine (CAS 1803823-77-9)
- Methyl 3-nonenoate (CAS 13481-87-3)
- 3-Cyclopropoxy-6-isopropyl-2-(methylthio)pyridine (CAS 1243468-81-6)
- 4-((4-((6-Acetoxyhexyl)oxy)benzoyl)oxy)-3-chlorophenyl 4-((6-(acryloyloxy)hexyl)oxy)benzoate (CAS 335380-15-9)
- {[1-(bromomethyl)cyclopropyl]methyl}benzene (CAS 863506-85-8)
- 2-(3-Methoxy-5-(trifluoromethyl)phenyl)acetonitrile (CAS 916421-02-8)
- Thiamine Impurity 33 (CAS 861031-76-7)
- Oleoyl chloride (CAS 112-77-6)
- Semaglutide impurity 85 (CAS CATO-C4X-222685)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com