Isavuconazole Impurity 66 CAS 258513-41-6
| CAS No. | 258513-41-6 |
| Molecular Formula | C8H5BrF2O |
| Molecular Weight | 235.03 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Isavuconazole Impurity 66.
Isavuconazole Impurity 66 (CAS 258513-41-6) is a certified pharmaceutical impurity reference standard with the molecular formula C8H5BrF2O and a molecular weight of 235.03 g/mol.
Owing to a hydroxyl group, an ether linkage, fluorine/bromine substitution, an aromatic ring system, Isavuconazole Impurity 66 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 235.03 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Isavuconazole Impurity 66 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H5BrF2O |
| Molecular Weight | 235.03 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Br-containing |
Related Isavuconazole Standards
- Isavuconazole Impurity 106 (CAS 150803-17-1)
- Isavuconazole Impurity 112 (CAS CATO-C4X-1236112)
- Isavuconazole impurity 214 (CAS CATO-C4X-1236214)
- Isavuconazole Impurity 215 (CAS CATO-C4X-1236215)
- Isavuconazole Impurity 222 (CAS CATO-C4X-1236222)
- Isavuconazole Impurity 224 (CAS CATO-C4X-1236224)
- Isavuconazole Impurity 43 (CAS CATO-C4X-123643)
- Isavuconazole Impurity 31 (CAS 20099-89-2)
Recommended Standards
- 4-Amino-6-iodo-2-methylpyrimidine 943006-46-0 C5H6IN3 W9672 (CAS 943006-46-0)
- 2-(4-Bromo-3-nitro-1H-pyrazol-1-yl)ethan-1-amine (CAS 1006950-44-2)
- 4-pyrimidinamine, 5-iodo-6-methyl- 5-Iodo-6-methylpyrimidin-4-amine 5-iodo-6-methyl-4-pyrimidinamine 5-iodo-6-methyl-4-pyrimidinylamine 83410-18-8 (CAS 83410-18-8)
- 3-(2,4-Dichloro-5-fluorophenyl)-3-oxopropanal (CAS 1179276-80-2)
- Bromocriptine Impurity 16 (CAS CATO-C4X-136116)
- Linezolid Impurity 87 (CAS 238418-75-2)
- Xanomeline impurity 56 (CAS CATO-C4X-330156)
- 2-Methyl-3-(methylsulfanyl)propan-1-ol (CAS 476301-86-7)
- 2-Methyl-5-(trifluoromethyl)nicotinonitrile (CAS 1346537-89-0)
- 4-Bromopyridine-2-carboximidamide hydrochloride (CAS 1179360-58-7)
- ethyl 2-sulfamoylpentanoate (CAS 1554858-29-5)
- 2-(4-Amino-2-methylphenoxy)acetamide (CAS 861294-91-9)
- 5-(Trifluoromethyl)-1-[3-(trifluoromethyl)phenyl]-1h-pyrazole-4-carboxylic acid (CAS 98534-85-1)
- Neuropeptide Y (18-36) (CAS 114495-97-5)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com