Isavuconazole Impurity 31 CAS 20099-89-2
| CAS No. | 20099-89-2 |
| Molecular Formula | C9H6BrNO |
| Molecular Weight | 224.05 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 224.05 g/mol gives Isavuconazole Impurity 31 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
As a process- or degradation-related impurity, Isavuconazole Impurity 31 (CAS 20099-89-2, C9H6BrNO) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Isavuconazole Impurity 31 (C9H6BrNO) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution. The molecule exhibits a degree of unsaturation (DBE) of 7.0, corresponding to approximately 7 ring(s) or double-bond equivalent(s). With a molecular weight of 224.05 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Isavuconazole Impurity 31 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H6BrNO |
| Molecular Weight | 224.05 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1962 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 1 |
Related Isavuconazole Standards
- Isavuconazole Impurity 61 (CAS 683274-86-4)
- Isavuconazole Impurity 224 (CAS CATO-C4X-1236224)
- Isavuconazole Impurity N16 (CAS 2491-38-5)
- Isavuconazole Impurity 106 (CAS 150803-17-1)
- Isavuconazole Impurity 112 (CAS CATO-C4X-1236112)
- Isavuconazole Impurity 181 (CAS CATO-C4X-1236181)
- Isavuconazole Impurity 66 (CAS 258513-41-6)
- Isavuconazole impurity 214 (CAS CATO-C4X-1236214)
Recommended Standards
- Bedaquiline impurity 42 (CAS 90279-39-3)
- Bedaquiline impurity 41 (CAS 860720-24-7)
- (6-(3-(Dimethylamino)propoxy)pyridin-3-yl)boronic acid (CAS 1003043-49-9)
- 850832-54-1 Methyl 4-bromo-5-methyl-1,2-oxazole-3-carboxylate DTXSID80649350 (CAS 850832-54-1)
- Tetrabenazine Impurity 3 (CAS 99672-64-7)
- Gadobutrol impurity 176 (CAS CATO-C4X-2120176)
- Brimonidine Impurity 15 (CAS 91147-46-5)
- 5-Heptyl-2-(4'-(pentyloxy)-[1,1'-biphenyl]-4-yl)pyrimidine (CAS 107215-52-1)
- 1-(Anthracen-2-yl)ethan-1-amine (CAS 102691-87-2)
- 2-Ethylhexane-1,3-diyl diacrylate (CAS 67905-08-2)
- 3-Methoxy-4-methylbenzoic Acid (CAS 7151-68-0)
- Mazokalim (CAS 164178-54-5)
- 4-(Methoxymethyl)benzonitrile (CAS 1515-85-1)
- endo-Ser39-Tirzepatide (CAS CATO-CPTD788935)
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