2,4-Dichloro-6-methoxy-3-nitroquinoline CAS 259180-83-1
| CAS No. | 259180-83-1 |
| Molecular Formula | C10H6Cl2N2O3 |
| Molecular Weight | 273.07 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 2,4-Dichloro-6-methoxy-3-nitroquinoline (CAS 259180-83-1), a certified reference material (molecular formula C10H6Cl2N2O3, MW 273.07 g/mol) for analytical method development and quality control.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, 2,4-Dichloro-6-methoxy-3-nitroquinoline is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 273.07 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H6Cl2N2O3 |
| Molecular Weight | 273.07 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Dichloro Standards
- 2,4-Dichloro-7-methoxy-3-nitroquinoline (CAS 1447961-41-2)
- 2,4-Dichloro-5-(fluorosulfonyl)benzoic acid (CAS 33866-08-9)
- Methyl 6,8-dichloro-2-oxo-2H-chromene-3-carboxylate (CAS 947264-93-9)
- Methyl 7,9-dichloro-4-oxo-4h-pyrido[1,2-a]pyrimidine-2-carboxylate (CAS 2007920-66-1)
- 3,5-Dichloro-6-(3-fluorophenyl)-1-methylpyrazin-2(1H)-one (CAS 1269529-93-2)
- 3,5-Dichloro-6-(4-fluorophenyl)-1-methylpyrazin-2(1H)-one (CAS 1269530-80-4)
- 3,5-Dichloro-6-(2-fluorophenyl)-1-methylpyrazin-2(1H)-one (CAS 1269533-60-9)
- 4,5-Dichloro-2-(2-fluorobenzyl)pyridazin-3(2h)-one (CAS 175135-46-3)
Recommended Standards
- 2-Bromo-4-(trifluoromethoxy)benzenethiol (CAS 875143-35-4)
- 2,3-Dihydro-6-iodoquinolin-4(1h)-one (CAS 38470-27-8)
- 2-Bromo-6-(difluoromethoxy)naphthalene (CAS 244103-47-7)
- 1-(3,4-Dichlorophenyl)-2,4,6(1H,3H,5H)-pyrimidinetrione (CAS 340300-14-3)
- 4-Iodo-3-(trifluoromethyl)benzamide (CAS 1261747-99-2)
- 1-(3-Methylpyridin-2-yl)propan-1-amine dihydrochloride (CAS 2061979-76-6)
- 2-(((4-Bromophenyl)amino)methyl)-6-methoxyphenol (CAS 196081-75-1)
- N-(5-Amino-2-fluorophenyl)-2-(3-methylphenoxy)-propanamide (CAS 954574-23-3)
- 2-(tert-Butoxy)-4-(tert-butyl)phenol (CAS 74831-57-5)
- Captopril Impurity 32 (CAS 65167-28-4)
- 8-Nitro-1,2,3,4,5,9b-hexahydrobenzo[c]thieno[2,1-e]isothiazole 4-oxide (CAS 2169311-00-4)
- 4-Bromo-6-methyl-2-(trifluoromethyl)quinoline (CAS 18706-27-9)
- 4-Bromobutaneboronic acid (1S,2S,3R,5S)-(+)-2,3-pinanediol ester (CAS 165881-36-7)
- Liraglutide Impurity 28 (CAS CATO-C4X-199228)
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