Captopril Impurity 32 CAS 65167-28-4
| CAS No. | 65167-28-4 |
| Molecular Formula | C11H17NO4S |
| Molecular Weight | 259.32 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a process- or degradation-related impurity, Captopril Impurity 32 (CAS 65167-28-4, C11H17NO4S) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C11H17NO4S, Captopril Impurity 32 contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 259.32 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), Captopril Impurity 32 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H17NO4S |
| Molecular Weight | 259.32 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1975 |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Captopril Standards
- Captopril Impurity J Hydrate Salt (CAS 801293-45-8)
- Captopril EP Impurity J (CAS 64838-55-7)
- Captopril EP Impurity B (CAS 80629-35-2)
- Captopril Impurity 40 (CAS 122130-63-6)
- Captopril EP Impurity N (CAS 65134-74-9)
- Captopril Methyl Ester (CAS 176036-41-2)
- Captopril-d3 (CAS 1356383-38-4)
- Captopril Impurity N1 (CAS 80141-53-3)
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- (2-fluorophenyl)(trifluoromethyl)sulfane (CAS 1978-16-1)
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