1-Bromo-2-(difluoromethoxy)-3-nitrobenzene CAS 259243-49-7
| CAS No. | 259243-49-7 |
| Molecular Formula | C7H4BrF2NO3 |
| Molecular Weight | 268.01 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1-Bromo-2-(difluoromethoxy)-3-nitrobenzene.
1-Bromo-2-(difluoromethoxy)-3-nitrobenzene (CAS 259243-49-7), molecular formula C7H4BrF2NO3 and molecular weight 268.01 g/mol, is a CATO reference standard with documented purity and traceability.
1-Bromo-2-(difluoromethoxy)-3-nitrobenzene (C7H4BrF2NO3) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/bromine substitution, an aromatic ring system. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 1-Bromo-2-(difluoromethoxy)-3-nitrobenzene under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C7H4BrF2NO3 |
| Molecular Weight | 268.01 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 1 |
Related Bromo Standards
- 2-Bromo-1-(difluoromethoxy)-3-nitrobenzene (CAS 1174315-54-8)
- 1-Bromo-3-(difluoromethoxy)-5-nitrobenzene (CAS 1261441-47-7)
- 4-Bromo-1-(difluoromethoxy)-2-nitrobenzene (CAS 1261552-41-3)
- 4-Bromo-2-(difluoromethoxy)-1-nitrobenzene (CAS 1261849-33-5)
- 3-Bromo-2-fluoro-5-(trifluoromethyl)benzonitrile (CAS 133013-32-8)
- 6-Bromo-2-fluoro-3-(trifluoromethyl)benzonitrile (CAS 1802370-84-8)
- 6-Bromo-5-(difluoromethyl)-4-hydroxypicolinic acid (CAS 1804652-86-5)
- 4-Bromo-5-(difluoromethyl)-3-hydroxypicolinic acid (CAS 1804652-97-8)
Recommended Standards
- 1-(Bromodifluoromethoxy)-4-nitrobenzene (CAS 81932-04-9)
- 1-Bromo-2-(difluoromethoxy)-4-nitrobenzene (CAS 835633-47-1)
- 4-Bromo-6-(difluoromethyl)-5-hydroxypicolinic acid (CAS 1806068-27-8)
- 1-Bromo-4-(difluoromethoxy)-2-nitrobenzene (CAS 865886-84-6)
- 3-(3,4-Dimethoxyphenyl)-5-((3-fluorobenzyl)thio)-4H-1,2,4-triazol-4-amine (CAS 676642-55-0)
- 4-Bromo-2-chloro-6-(difluoromethyl)nicotinic acid (CAS 1805232-02-3)
- Phenyl (2,9-dimethyl-1,10-phenanthrolin-5-yl)carbamate (CAS 376649-62-6)
- Ethyl 3-(hydroxymethyl)benzoate (CAS 34841-13-9)
- (Z)-7-((1R,2S)-2-((R,E)-3-Hydroxy-4-phenoxybut-1-en-1-yl)-5-oxocyclopent-3-en-1-yl)hept-5-enoic acid (CAS 51639-10-2)
- 7-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)dibenzo[c,h]acridine (CAS 1441062-49-2)
- 2-(2-Hydroxy-2-methylpropyl)cyclohexan-1-ol (CAS 91008-63-8)
- 4-Acetoxy-3-iodobenzoic acid (CAS 190067-59-5)
- 2,3-Dihydroxysuccinonitrile (CAS 76110-75-3)
- Semaglutide impurity 249 (CAS CATO-C4X-2226249)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com