LCZ-696 Impurity 78 CAS 2605-68-7

Purity >95%In StockPharmacopoeial Impurity Standards
CAS No.2605-68-7
Molecular FormulaC22H21O2P
Molecular Weight348.37 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

LCZ-696 Impurity 78 CAS 2605-68-7 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including LCZ-696 Impurity 78.

CATO supplies LCZ-696 Impurity 78 (CAS 2605-68-7), a pharmacopoeial impurity reference standard (molecular formula C22H21O2P, MW 348.37 g/mol) used for the identification and quantification of trace impurities in APIs.

LCZ-696 Impurity 78 (C22H21O2P) contains a steroid core, organophosphorus functionality, a hydroxyl group, an ether linkage. Its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

CATO manufactures LCZ-696 Impurity 78 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC22H21O2P
Molecular Weight348.37 g/mol
AppearancePale yellow to yellow crystalline powder
Purity>95%
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)12.5
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1957

Recommended Standards

Why CATO?