Dasatinib Impurity 69 CAS CATO-C4X-160769
| CAS No. | CATO-C4X-160769 |
| Molecular Formula | C23H28ClN7O2S |
| Molecular Weight | 502.03 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Dasatinib Impurity 69 (CAS CATO-C4X-160769) is a certified pharmaceutical impurity reference standard with the molecular formula C23H28ClN7O2S and a molecular weight of 502.03 g/mol.
Owing to a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution, Dasatinib Impurity 69 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 502.03 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C23H28ClN7O2S |
| Molecular Weight | 502.03 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 7 |
| Sulfur Atoms | 1 |
Related Dasatinib Standards
- Dasatinib Impurity 4 (CAS 910297-53-9)
- Dasatinib Impurity 12 (CAS 910297-57-3)
- Dasatinib Impurity 15 (CAS 910297-58-4)
- Dasatinib Impurity 2 (CAS 910297-52-8)
- Dasatinib Impurity 47 (CAS CATO-C4X-160747)
- Dasatinib-d8 (CAS 1132093-70-9)
- Dasatinib impurity 63 (CAS CATO-C4X-160763)
- Dasatinib D4 (CAS 1160297-08-4)
Recommended Standards
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