2-(thiophen-2-yl)-3,4-dihydroquinazolin-4-one CAS 26059-85-8

Description

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

2-(thiophen-2-yl)-3,4-dihydroquinazolin-4-one (CAS 26059-85-8) is a high-purity analytical reference standard with the molecular formula C12H8N2OS and a molecular weight of 228.27 g/mol.

Structurally, 2-(thiophen-2-yl)-3,4-dihydroquinazolin-4-one (C12H8N2OS) contains a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 10.0, corresponding to approximately 10 ring(s) or double-bond equivalent(s). With a molecular weight of 228.27 g/mol, it falls into the medium-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

As a certified reference material (CRM), 2-(thiophen-2-yl)-3,4-dihydroquinazolin-4-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

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