(E)-4-(thiophen-2-yl)-2,3-dihydro-1H-benzo[b][1,4]diazepine 4-(2-Thienyl)-2,3-dihydro-1H-1,5-benzodiazepine 497178-55-9 CAS 497178-55-9
| CAS No. | 497178-55-9 |
| Molecular Formula | C13H12N2S |
| Molecular Weight | 228.31 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including (E)-4-(thiophen-2-yl)-2,3-dihydro-1H-benzo[b][1,4]diazepine 4-(2-Thienyl)-2,3-dihydro-1H-1,5-benzodiazepine 497178-55-9.
(E)-4-(thiophen-2-yl)-2,3-dihydro-1H-benzo[b][1,4]diazepine 4-(2-Thienyl)-2,3-dihydro-1H-1,5-benzodiazepine 497178-55-9 (CAS 497178-55-9), molecular formula C13H12N2S and molecular weight 228.31 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of (E)-4-(thiophen-2-yl)-2,3-dihydro-1H-benzo[b][1,4]diazepine 4-(2-Thienyl)-2,3-dihydro-1H-1,5-benzodiazepine 497178-55-9 (C13H12N2S) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C13H12N2S |
| Molecular Weight | 228.31 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
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- 1-(3-Bromo-4-fluorophenyl)butane-1,3-dione (CAS 1020042-58-3)
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- Methisosildenafil Impurity 3 (CAS 639068-43-2)
- (2-Azabicyclo[4.1.0]Heptan-5-yl)methanol hydrochloride (CAS 2387596-67-8)
- Methyl 3-{[(1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-3-yl)carbamoyl]amino}benzoate (CAS 1796916-18-1)
- Semaglutide impurity 107 (CAS CATO-C4X-2226107)
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