1-Chloro-2,3,4,5-tetramethylbenzene CAS 26138-77-2
| CAS No. | 26138-77-2 |
| Molecular Formula | C10H13Cl |
| Molecular Weight | 168.66 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 1-Chloro-2,3,4,5-tetramethylbenzene (C10H13Cl) is characterized by chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
1-Chloro-2,3,4,5-tetramethylbenzene (CAS 26138-77-2) is a high-purity analytical reference standard with the molecular formula C10H13Cl and a molecular weight of 168.66 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H13Cl |
| Molecular Weight | 168.66 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1964 |
| Halogen Content | Cl-containing |
Related Chloro Standards
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Recommended Standards
- 1-(tert-Butyl)-3-chlorobenzene (CAS 3972-55-2)
- 1-(tert-Butyl)-2-chlorobenzene (CAS 7073-98-5)
- 1-tert-Butyl-4-chlorobenzene (CAS 3972-56-3)
- 1-(chloromethyl)-4-propylbenzene (CAS 3166-97-0)
- 6-Methoxy-4-methylbenzo[d]thiazol-2-amine (CAS 331679-72-2)
- meso-Tetrakis(4-chlorophenyl)porphyrin-Ni(II) (CAS 57774-14-8)
- rac-trans-[3-Hydroxycyclohexyl]benzamide (CAS 177366-90-4)
- 4-Methyl-1H-indol-5-amine (CAS 196205-06-8)
- Revefenacin Impurity 5 (CAS CATO-C4X-20315)
- 4-Acetyl-2-amino-5-methylthiazole (CAS 40353-62-6)
- 2-cyclobutylpropanoic acid (CAS 1082453-55-1)
- Glycopyrronium Bromide Impurity 7 (CAS 1404453-68-4)
- Chlortetracycline EP Impurity A (CAS 14297-93-9)
- D-[Val]10-Semaglutide (CAS CATO-CPTD788630)
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