N-Trifluoroacetyl Deacetylcolchicine CAS 26195-65-3
| CAS No. | 26195-65-3 |
| Molecular Formula | C22H22F3NO6 |
| Molecular Weight | 453.41 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 453.41 g/mol gives N-Trifluoroacetyl Deacetylcolchicine distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies N-Trifluoroacetyl Deacetylcolchicine (CAS 26195-65-3), a certified reference material (molecular formula C22H22F3NO6, MW 453.41 g/mol) for analytical method development and quality control.
The molecular framework of N-Trifluoroacetyl Deacetylcolchicine (C22H22F3NO6) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures N-Trifluoroacetyl Deacetylcolchicine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C22H22F3NO6 |
| Molecular Weight | 453.41 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1964 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related N Standards
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Recommended Standards
- 1217782-80-3 2,2,2-Trifluoro-N-methyl-N-[(7S)-5,6,7,9-tetrahydro-10-hydroxy-1,2,3-trimethoxy-9-oxobenzo[a]heptalen-7-yl]acetamide N-Trifluoroacetyl-N-methyl-deacetylcolchiceine (CAS 1217782-80-3)
- N-Trifluoroacetyliso Deacetylcolchicine (CAS 71324-48-6)
- 2,2,2-Trifluoro-N-(5,6,7,10-tetrahydro-1,2,3,9-tetramethoxy-10-oxobenzo[a]heptalen-7-yl)acetamide (CAS 102491-72-5)
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- 2-(Aminomethyl)-3-(difluoromethyl)-5-fluoropyridine-6-carboxylic acid (CAS 1805996-30-8)
- 1,2-Dioctanoyl-sn-glycerol 3-Phosphate Sodium Salt (CAS 178603-80-0)
- Tert-butyl (4-fluorobenzo[d]isoxazol-3-yl)carbamate (CAS 1344688-29-4)
- methyl 3-amino-4-(propan-2-yl)benzoate (CAS 24830-44-2)
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- 2-Iodo-9-methoxy-5,6-dihydrobenzo[f]imidazo[1,2-d][1,4]oxazepine (CAS 1956376-94-5)
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- Methyl 2-(Bromomethyl)benzothiazole-5-carboxylate (CAS 1227628-99-0)
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Why CATO?
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