Hydroxychloroquine Impurity 37 CAS CATO-C4X-183537
| CAS No. | CATO-C4X-183537 |
| Molecular Formula | C25H26Cl2N4 |
| Molecular Weight | 453.41 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 453.41 g/mol gives Hydroxychloroquine Impurity 37 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Hydroxychloroquine Impurity 37 (CAS CATO-C4X-183537) is a certified pharmaceutical impurity reference standard with the molecular formula C25H26Cl2N4 and a molecular weight of 453.41 g/mol.
Structurally, Hydroxychloroquine Impurity 37 (C25H26Cl2N4) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 14.0, corresponding to approximately 14 ring(s) or double-bond equivalent(s). With a molecular weight of 453.41 g/mol, it falls into the moderately-high-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C25H26Cl2N4 |
| Molecular Weight | 453.41 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related Hydroxychloroquine Standards
- Hydroxychloroquine impurity 82 (CAS CATO-C4X-183582)
- Hydroxychloroquine Impurity 44 (CAS CATO-C4X-183544)
- Hydroxychloroquine Impurity 39 (CAS CATO-C4X-183539)
- Hydroxychloroquine Impurity 41 (CAS CATO-C4X-183541)
- Hydroxychloroquine Impurity 42 (CAS CATO-C4X-183542)
- Hydroxychloroquine Impurity 30 (CAS CATO-C4X-183530)
- Hydroxychloroquine EP Impurity B (CAS 103152-84-7)
- Hydroxychloroquine Impurity 43 (CAS CATO-C4X-183543)
Recommended Standards
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- N-Trifluoroacetyl Deacetylcolchicine (CAS 26195-65-3)
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- (e)-3-(1h-Indol-3-yl)prop-2-en-1-ol (CAS 21777-20-8)
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- Convallatoxin (CAS 508-75-8)
- Gly-Neuroendocrine Regulatory Peptide-3 (human, mouse, rat) trifluoroacetate salt (CAS 1815618-19-9)
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