4-Bromothiazole-5-methanol CAS 262444-15-5
| CAS No. | 262444-15-5 |
| Molecular Formula | C4H4BrNOS |
| Molecular Weight | 194.05 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 4-Bromothiazole-5-methanol (C4H4BrNOS) is characterized by an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
4-Bromothiazole-5-methanol (CAS 262444-15-5), molecular formula C4H4BrNOS and molecular weight 194.05 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 4-Bromothiazole-5-methanol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C4H4BrNOS |
| Molecular Weight | 194.05 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Bromothiazole Standards
- 4-Bromothiazole-5-carbaldehyde (CAS 1244948-92-2)
- 4-Bromothiazole-2-carboxaldehyde (CAS 167366-05-4)
- 5-Bromothiazole-2-carbaldehyde, 97% (CAS 933752-44-4)
- 5-Bromothiazole-4-carbaldehyde (CAS 934346-19-7)
- 5-Bromothiazole-2(3H)-thione (CAS 63329-71-5)
- 5-Bromothiazole-4-carbonitrile (CAS 1257072-06-2)
- 4-Bromothiazole-5-carbonitrile (CAS 1367964-98-4)
- 2-Bromothiazole-5-carbonitrile (CAS 440100-94-7)
Recommended Standards
- 4-Bromo-5-methylisothiazol-3(2H)-one (CAS 25629-53-2)
- 5-Bromo-2-(hydroxymethyl)thiazole (CAS 911052-85-2)
- 4-Bromo-3-methoxy-1,2-thiazole (CAS 31815-40-4)
- 5-Bromo-2-methoxy-1,3-thiazole (CAS 446287-05-4)
- 4-Phenyl-5-(2-phenylethyl)-4h-1,2,4-triazol-3-yl hydrosulfide (CAS 114246-71-8)
- 1-(2-Chlorophenyl)imidazoline-2-thione (CAS 51581-47-6)
- 2-{[(4-chlorophenyl)methoxy]methyl}oxirane (CAS 66931-55-3)
- 1-[4-(Pyrrolidin-1-ylmethyl)phenyl]ethanone (CAS 149704-65-4)
- Ethyl 4-ethoxy-2,6,6-trimethylcyclohexa-1,3-dienecarboxylate (CAS 23115-91-5)
- [3-(1H-Imidazol-1-yl)propyl][(pyridin-4-yl)methyl]amine dihydrochloride (CAS 279236-32-7)
- N-[2-(1-Cyclohexen-1-yl)ethyl]-1-propanaminehydrochloride (CAS 356532-69-9)
- 2-(2-Bromophenoxy)propanamide (CAS 915920-68-2)
- 4-Amino-5-bromo-2-ethoxybenzoic acid (CAS 84923-73-9)
- Semaglutide impurity 200 (CAS CATO-C4X-2226200)
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