4-(Pyridin-4-ylethynyl)-1-naphthoic acid CAS 2627156-73-2

Purity 97%+In StockPharmaceutical Standards
CAS No.2627156-73-2
Molecular FormulaC18H11NO2
Molecular Weight273.29 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

4-(Pyridin-4-ylethynyl)-1-naphthoic acid CAS 2627156-73-2 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 273.29 g/mol gives 4-(Pyridin-4-ylethynyl)-1-naphthoic acid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

4-(Pyridin-4-ylethynyl)-1-naphthoic acid (CAS 2627156-73-2), molecular formula C18H11NO2 and molecular weight 273.29 g/mol, is a CATO reference standard with documented purity and traceability.

4-(Pyridin-4-ylethynyl)-1-naphthoic acid (C18H11NO2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage. Its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 4-(Pyridin-4-ylethynyl)-1-naphthoic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC18H11NO2
Molecular Weight273.29 g/mol
AppearancePale yellow to yellow crystalline powder
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)14.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2001
Nitrogen Atoms1

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