3-bromo-5,7-dichloro-1,6-naphthyridine CAS 2629163-50-2
| CAS No. | 2629163-50-2 |
| Molecular Formula | C8H3BrCl2N2 |
| Molecular Weight | 277.93 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 3-bromo-5,7-dichloro-1,6-naphthyridine is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine/bromine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
3-bromo-5,7-dichloro-1,6-naphthyridine (CAS 2629163-50-2) is a high-purity analytical reference standard with the molecular formula C8H3BrCl2N2 and a molecular weight of 277.93 g/mol.
The molecular framework of 3-bromo-5,7-dichloro-1,6-naphthyridine (C8H3BrCl2N2) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine/bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 3-bromo-5,7-dichloro-1,6-naphthyridine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H3BrCl2N2 |
| Molecular Weight | 277.93 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2001 |
| Halogen Content | Cl/Br-containing |
| Nitrogen Atoms | 2 |
Related bromo Standards
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Recommended Standards
- 2-Bromo-6,7-dichloroquinazoline (CAS 2090315-34-5)
- 4-Bromo-1,6-dichloro-2,7-naphthyridine (CAS 2385502-17-8)
- 2-Bromo-5,7-dichloro-1,6-naphthyridine (CAS 2837942-08-0)
- 6-Bromo-1,4-dichlorophthalazine (CAS 240400-95-7)
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