2-Chloro-5-ethynylpyridine CAS 263012-63-1
| CAS No. | 263012-63-1 |
| Molecular Formula | C7H4ClN |
| Molecular Weight | 137.57 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-Chloro-5-ethynylpyridine (CAS 263012-63-1) is a high-purity analytical reference standard with the molecular formula C7H4ClN and a molecular weight of 137.57 g/mol.
2-Chloro-5-ethynylpyridine (C7H4ClN) contains a nitrile group, chlorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 2-Chloro-5-ethynylpyridine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H4ClN |
| Molecular Weight | 137.57 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- 4-Chloro-2-ethynylpyridine (CAS 1010115-57-7)
- 1-Chloro-2-isocyanobenzene (CAS 10432-84-5)
- 4-Chloro-3-ethynylpyridine (CAS 1196145-03-5)
- 5-Chloro-2-ethynylpyridine (CAS 1196153-33-9)
- 2-Chloro-3-ethynylpyridine (CAS 1196156-69-0)
- 3-Chloro-4-ethynylpyridine (CAS 1379109-40-6)
- 1-Chloro-4-isocyanobenzene (CAS 1885-81-0)
- 1-CHloro-3-isocyanobenzene (CAS 32686-54-7)
Recommended Standards
- 2-Chloro-4-ethynylpyridine (CAS 945717-09-9)
- 2-Chloro-6-ethynylpyridine (CAS 914950-09-7)
- 3-Chloro-2-ethynylpyridine (CAS 96439-98-4)
- 4-Chlorobenzonitrile (CAS 623-03-0)
- 1-(4-Trifluoromethylphenyl)allylamine (CAS 1159883-01-8)
- (2R,3S)-2-Carboxy-3-hydroxypyrrolidin-1-ium 2,2,2-trifluoroacetate (CAS 1818843-17-2)
- 5-Chloroquinoline-8-carboxamide (CAS 1824025-22-0)
- 5-(3-(Aminomethyl)-1,2,4-oxadiazol-5-yl)pyrrolidin-2-one (CAS 1674433-87-4)
- [(5-Chlorothiophen-2-yl)(pyridin-3-yl)methyl](ethyl)amine (CAS 1154233-62-1)
- 4-Cyclopropylthiophenylboronic acid (CAS 411229-80-6)
- 1-Methyl-4-(1-methylcyclohexyl)benzene (CAS 14962-12-0)
- 2-(Difluoromethyl)-3-methoxy-5-methylpyridine-4-carbonyl chloride (CAS 1807165-24-7)
- 3-Chloro-1-(4-methoxyphenyl)-4-(m-tolylamino)-1H-pyrrole-2,5-dione (CAS 61892-19-1)
- Atrial Natriuretic Polypeptide (4-28), human (CAS 95896-08-5)
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