4-Chlorobenzonitrile CAS 623-03-0
| CAS No. | 623-03-0 |
| Molecular Formula | C7H4ClN |
| Molecular Weight | 137.57 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 137.57 g/mol gives 4-Chlorobenzonitrile distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies 4-Chlorobenzonitrile (CAS 623-03-0), a certified reference material (molecular formula C7H4ClN, MW 137.57 g/mol) for analytical method development and quality control.
Owing to a nitrile group, chlorine substitution, an aromatic ring system, 4-Chlorobenzonitrile is typically off-white to pale yellow liquid. Its solid-state physicochemical attributes — including a molecular weight of 137.57 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 4-Chlorobenzonitrile meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H4ClN |
| Molecular Weight | 137.57 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Chlorobenzonitrile Standards
- 3-Chlorobenzonitrile (CAS 766-84-7)
- 2-Chlorobenzonitrile (CAS 873-32-5)
- 4-Chlorobenzonitrile-d4 (CAS 1219794-82-7)
- 4-Acetyl-2-chlorobenzonitrile (CAS 101667-74-7)
- 4-acetyl-3-chlorobenzonitrile (CAS 1096666-21-5)
- 3-Acetyl-4-chlorobenzonitrile (CAS 120569-07-5)
- 3-Acetyl-5-chlorobenzonitrile (CAS 1393581-95-7)
- 5-Acetyl-2-chlorobenzonitrile (CAS 68505-13-5)
Recommended Standards
- 3-Chloro-2-ethynylpyridine (CAS 96439-98-4)
- 2-Chloro-6-ethynylpyridine (CAS 914950-09-7)
- 2-Chloro-5-ethynylpyridine (CAS 263012-63-1)
- 3-chloro-5-fluoro-pyridine (CAS 514797-99-0)
- 3-Bromo-6,6-difluoro-2-(4-fluorophenyl)-6,7-dihydro-5H-pyrazolo[5,1-b][1,3]oxazine (CAS 1429893-30-0)
- Ethyl 5-ethoxy-2-hydroxybenzoate (CAS 14160-70-4)
- N-((2R,3R,4S,5R)-3,4,5,6-tetrahydroxy-1-oxohexan-2-yl)butyramide (CAS 5441-12-3)
- N-benzyl-1-(2-(pyrrolidin-1-yl)pyrimidin-5-yl)methanamine (CAS 1279217-13-8)
- 4-Bromo-3-fluorotoluene (CAS 452-74-4)
- 4-(1,4-Diazepan-1-yl)-5,6-dimethylthieno-[2,3-d]pyrimidine (CAS 874776-29-1)
- 3-[(3,5-Dichloro-4-hydroxy-benzylidene)-hydrazono]-5-methoxy-1,3-dihydro-indol-2-one (CAS 1380572-53-1)
- N-Ethyl-3-fluoro-5-hydroxybenzamide (CAS 1881320-67-7)
- (3-(((Benzyloxy)carbonyl)amino)-5-nitrophenyl)boronic acid (CAS 874219-56-4)
- Semaglutide impurity 256 (CAS CATO-C4X-2226256)
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