N'-[(6-chloropyridin-3-yl)carbonyl]-4-(trifluoromethyl)benzohydrazide CAS 263563-39-9
| CAS No. | 263563-39-9 |
| Molecular Formula | C14H9ClF3N3O2 |
| Molecular Weight | 343.69 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), N'-[(6-chloropyridin-3-yl)carbonyl]-4-(trifluoromethyl)benzohydrazide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
N'-[(6-chloropyridin-3-yl)carbonyl]-4-(trifluoromethyl)benzohydrazide (CAS 263563-39-9), molecular formula C14H9ClF3N3O2 and molecular weight 343.69 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of N'-[(6-chloropyridin-3-yl)carbonyl]-4-(trifluoromethyl)benzohydrazide (C14H9ClF3N3O2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C14H9ClF3N3O2 |
| Molecular Weight | 343.69 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
Related N Standards
- 1-(4-Chloropyridin-2-yl)-2,2,2-trifluoroethyl trifluoromethanesulfonate (CAS 1356087-54-1)
- 2-{[(6-chloropyridin-3-yl)methyl]sulfanyl}-6-methyl-4-(trifluoromethyl)pyridine-3-carbonitrile (CAS 674805-54-0)
- Ethyl 2-(2-(2-chloropyridin-3-yl)-5,6-dimethyl-1H-benzo[d]imidazol-1-yl)acetate (CAS 344278-84-8)
- (6-Chloropyridin-3-yl)(2-iodophenyl)methanone (CAS 1187165-85-0)
- (6-Chloropyridin-3-yl)(3-iodophenyl)methanone (CAS 1187169-80-7)
- (6-Chloropyridin-3-yl)(4-iodophenyl)methanone (CAS 1187170-32-6)
- 3-(4-(6-Chloropyridin-3-yl)tetrahydro-2H-pyran-4-yl)-5-(pyridin-3-yl)-1,2,4-oxadiazole (CAS 1369513-99-4)
- 2-{[1-(6-chloropyridin-2-yl)-1H-1,2,4-triazol-3-yl]methoxy}benzohydrazide (CAS 338756-27-7)
Recommended Standards
- 2-Chloro-5-(3-(trifluoromethyl)benzamido)benzoic acid (CAS 896160-35-3)
- 4-(3-Chloro-4-fluorophenoxy)-6-nitroquinoline-3-carbonitrile (CAS 928779-54-8)
- 1-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl](methyl)amino}-6-methyl-4-oxo-1,4-dihydropyrimidine-5-carbonitrile (CAS 303153-05-1)
- N-(4-Chloro-3-nitrophenyl)-2-indol-3-yl-2-oxoethanamide (CAS 1024255-49-9)
- N-(3-acetylphenyl)-2-aminothiophene-3-carboxamide (CAS 590356-75-5)
- 2-(3-Bromophenyl)-2-cyclopropylacetic acid (CAS 1566779-24-5)
- 3-Chloroquinoline-7-carbonitrile (CAS 1431869-16-7)
- 2-Phenylmorpholine Hydrochloride (CAS 23972-42-1)
- 3-Methyl-1-(3,3,3-trifluoropropyl)piperidin-4-amine (CAS 1342244-02-3)
- 2-Methylthiazole-5-sulfonamide (CAS 519055-67-5)
- 1-(Furan-2-yl)-N-(pyridin-3-ylmethyl)methanamine hydrochloride (CAS 1052404-24-6)
- 5-Methoxy-2-nitrobenzoic acid-d3 (CAS 2098655-74-2)
- But-2-yne-1-sulfonyl chloride (CAS 1342209-39-5)
- D-Pro36-Tirzepatide (CAS CATO-CPTD788903)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com