3-(4-Chlorophenoxy)-7-hydroxy-2-(trifluoromethyl)-4h-chromen-4-one CAS 263744-91-8
| CAS No. | 263744-91-8 |
| Molecular Formula | C16H8ClF3O4 |
| Molecular Weight | 356.68 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures 3-(4-Chlorophenoxy)-7-hydroxy-2-(trifluoromethyl)-4h-chromen-4-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
3-(4-Chlorophenoxy)-7-hydroxy-2-(trifluoromethyl)-4h-chromen-4-one (CAS 263744-91-8) is a high-purity analytical reference standard with the molecular formula C16H8ClF3O4 and a molecular weight of 356.68 g/mol.
The molecular framework of 3-(4-Chlorophenoxy)-7-hydroxy-2-(trifluoromethyl)-4h-chromen-4-one (C16H8ClF3O4) is characterized by a flavonoid core, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C16H8ClF3O4 |
| Molecular Weight | 356.68 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
Related Chlorophenoxy Standards
- 3-(2-Chlorophenoxy)-7-hydroxy-2-(trifluoromethyl)-4H-chromen-4-one (CAS 459419-19-3)
- Methyl 4-(4-chlorophenoxy)-6-oxo-1-phenyl-1,6-dihydropyridazine-3-carboxylate (CAS 338756-21-1)
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- N-[4-(2-Chlorophenoxy)phenylsulfonyl]-DL-alanine (CAS 1008472-78-3)
- 3-((4-(2-Chlorophenoxy)phenyl)sulfonamido)propanoic acid (CAS 606945-29-3)
- Ethyl 5-(2-chlorophenoxy)-3-phenyl-1,2,4-triazine-6-carboxylate (CAS 338957-42-9)
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- 5-((4-Chlorophenoxy)methyl)-N-(3-methoxyphenyl)furan-2-carboxamide (CAS 879565-87-4)
Recommended Standards
- 2-(2-chloro-6-methylpyrimidin-4-yl)-5-[2-(trifluoromethoxy)phenyl]-1,3,4-oxadiazole (CAS 680216-49-3)
- 2-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methoxy}-2,3-dihydro-1H-isoindole-1,3-dione (CAS 321430-50-6)
- 2-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl](methyl)amino}-1H,2H,3H-pyrrolo[3,4-c]pyridine-1,3-dione (CAS 339098-51-0)
- 1-(2-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-2,2-difluoroacetyl)piperidin-4-one (CAS 1823182-56-4)
- 4-Chloro-2,5-difluorobenzene-1-sulfonamide (CAS 287172-62-7)
- 2-Methyl-2,3-dihydro-1H-indene (CAS 824-63-5)
- 2-Iodo-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine-6-carbonitrile (CAS 1227267-29-9)
- 1-Ethyl-2-((4-fluorobenzyl)thio)-5-(4-methoxyphenyl)-1H-imidazole (CAS 1207045-53-1)
- (3R)-3-methyltetrahydrofuran-3-carboxylic acid (CAS 2200475-49-4)
- 5-Amino-3H-pyrazolo[4,3-d]pyrimidin-7(4H)-one (CAS 369598-74-3)
- Desmopressin Impurity 21 (CAS CATO-C4X-221521)
- Letrozole Impurity 5 (CAS 32446-66-5)
- 1-(6-Bromohexyl)-1H-1,2,3-triazole (CAS 2006277-81-0)
- α Bag Cell Peptide (1-9) (CAS 87549-52-8)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com