2-Chloro-6-fluoro-3,4-bis((4-methoxybenzyl)oxy)benzoic acid CAS 2637445-13-5
| CAS No. | 2637445-13-5 |
| Molecular Formula | C23H20ClFO6 |
| Molecular Weight | 446.85 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
2-Chloro-6-fluoro-3,4-bis((4-methoxybenzyl)oxy)benzoic acid (CAS 2637445-13-5), molecular formula C23H20ClFO6 and molecular weight 446.85 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a flavonoid core, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, 2-Chloro-6-fluoro-3,4-bis((4-methoxybenzyl)oxy)benzoic acid is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 446.85 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), 2-Chloro-6-fluoro-3,4-bis((4-methoxybenzyl)oxy)benzoic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C23H20ClFO6 |
| Molecular Weight | 446.85 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2001 |
| Halogen Content | F/Cl-containing |
Related Chloro Standards
- N-(5-Chloro-3-(phenylsulfonyl)-1H-indol-2-yl)-2,4-difluorobenzamide (CAS 918493-42-2)
- 5-(5-Chloro-2-methoxybenzenesulfonyl)-8-(trifluoromethyl)-1H,2H,3H,3aH,4H,5H-pyrrolo[1,2-a]quinoxaline (CAS 861207-45-6)
- Methyl 6-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-2-[(E)-[(dimethylamino)methylidene]amino]-4H,5H,6H,7H-thieno[2,3-c]pyridine-3-carboxylate (CAS 321430-39-1)
- 2-[4-chloro-3-(trifluoromethyl)benzenesulfonamido]-3-(1h-indol-3-yl)propanoic acid (CAS 1009272-85-8)
- ((4-Chloro-3-(trifluoromethyl)phenyl)sulfonyl)-l-tryptophan (CAS 1212378-69-2)
- 2-Chloro-N-((4-methyl-2-(4-(trifluoromethyl)phenyl)thiazol-5-yl)methyl)benzenesulfonamide (CAS 866018-72-6)
- 3-(3-Chloro-2-methylphenyl)-N'-(4-methylbenzoyl)-4-oxo-3,4-dihydrophthalazine-1-carbohydrazide (CAS 866039-05-6)
- 3-(3-Chloro-2-methylphenyl)-N'-[(1E)-(3-methoxyphenyl)methylidene]-4-oxo-3,4-dihydrophthalazine-1-carbohydrazide (CAS 672949-04-1)
Recommended Standards
- Resmetirom impurity 87 (CAS CATO-C4X-291287)
- Resmetirom impurity 86 (CAS CATO-C4X-291286)
- 1-Methyl-2-(pentan-3-yl)quinolin-4(1H)-one (CAS 126365-17-1)
- Resmetirom Impurity 32 (CAS CATO-C4X-291232)
- (3-(Trifluoromethoxy)benzyl)hydrazine dihydrochloride (CAS 1427396-65-3)
- 2-(Aminomethyl)-2-(4-fluorobenzyl)cyclopentan-1-ol (CAS 1487806-27-8)
- 2-Isopropylthiophen-3-amine (CAS 106944-37-0)
- 2-((2-Carboxyphenyl)amino)-3-methoxybenzoic acid (CAS 88377-32-6)
- 4-(1,3-Dioxaindan-5-yl)-3-(cyclopropylmethyl)-1h-pyrazol-5-amine (CAS 1334340-22-5)
- n-Methyl-N-(4-methylbenzyl)methanesulfonamide (CAS 138468-22-1)
- 4-(3-Methyl-5-(trifluoromethyl)-1H-pyrazol-1-yl)aniline (CAS 374814-12-7)
- N,N-Dimethylquinolin-7-amine (CAS 89770-32-1)
- 2,3-Dichloro-5-nitrophenol (CAS 1806356-80-8)
- Acetyl Hexapeptide-39 (CAS 1382088-38-1)
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