Lincomycin EP Impurity D Hydrochloride(7-epi Lincomycin Hydrochloride) CAS 26389-84-4
| CAS No. | 26389-84-4 |
| Molecular Formula | C18H34N2O6S |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Lincomycin EP Impurity D Hydrochloride(7-epi Lincomycin Hydrochloride) is closely related to an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies Lincomycin EP Impurity D Hydrochloride(7-epi Lincomycin Hydrochloride) (CAS 26389-84-4), a pharmacopoeial impurity reference standard (molecular formula C18H34N2O6SHCl, MW 443.00 g/mol) used for the identification and quantification of trace impurities in APIs.
Lincomycin EP Impurity D Hydrochloride(7-epi Lincomycin Hydrochloride) (C18H34N2O6SHCl) contains an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C18H34N2O6S HCl |
| Molecular Weight | 443.00 g/mol |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1964 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Lincomycin Standards
- Lincomycin B Hydrochloride (CAS 11021-35-5)
- Lincomycin EP Impurity E (CAS 13380-36-4)
- Lincomycin EP Impurity C (CAS 14600-41-0)
- Lincomycin EP Impurity F (CAS 14810-93-6)
- Lincomycin EP Impurity F Dihydrate (CAS 14810-93-6(Anhydrate CAS))
- Lincomycin EP Impurity D(Clindamycin EP Impurity D) (CAS 17017-22-0)
- Lincomycin sulfone Impurity (CAS 198080-68-1)
- Lincomycin Sulfoxide (Mixture of Diastereomers) (CAS 22083-92-7)
Recommended Standards
- Relugolix Impurity 117 (CAS 2814571-35-0)
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- 2-Amino-1-(4-methoxybenzyl)-4,5,6,7-tetrahydro-1H-indole-3-carbonitrile (CAS 113772-12-6)
- 2-Chloro-6-methoxybenzamide (CAS 107485-43-8)
- Peptide Impurity (CAS CATO-CPTD788810)
Why CATO?
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