(+)-Methyl (3S)-5-{[tert-Butyldimethylsilyl)oxy]}-3-hydroxy-2,2-dimethylpentanoate (3S)-5-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]-3-hydroxy-2,2-dimethyl-pentanoic Acid Methyl Ester 263900-32-9 CAS 263900-32-9

Purity 97%+In StockPharmaceutical Standards
CAS No.263900-32-9
Molecular FormulaC14H30O4Si
Molecular Weight290.47 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

(+)-Methyl (3S)-5-{[tert-Butyldimethylsilyl)oxy]}-3-hydroxy-2,2-dimethylpentanoate (3S)-5-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]-3-hydroxy-2,2-dimethyl-pentanoic Acid Methyl Ester 263900-32-9 CAS 263900-32-9 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including (+)-Methyl (3S)-5-{[tert-Butyldimethylsilyl)oxy]}-3-hydroxy-2,2-dimethylpentanoate (3S)-5-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]-3-hydroxy-2,2-dimethyl-pentanoic Acid Methyl Ester 263900-32-9.

CATO supplies (+)-Methyl (3S)-5-{[tert-Butyldimethylsilyl)oxy]}-3-hydroxy-2,2-dimethylpentanoate (3S)-5-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]-3-hydroxy-2,2-dimethyl-pentanoic Acid Methyl Ester 263900-32-9 (CAS 263900-32-9), a certified reference material (molecular formula C14H30O4Si, MW 290.47 g/mol) for analytical method development and quality control.

The molecular framework of (+)-Methyl (3S)-5-{[tert-Butyldimethylsilyl)oxy]}-3-hydroxy-2,2-dimethylpentanoate (3S)-5-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]-3-hydroxy-2,2-dimethyl-pentanoic Acid Methyl Ester 263900-32-9 (C14H30O4Si) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC14H30O4Si
Molecular Weight290.47 g/mol
Purity97%+
StorageStore in a cool place (≤25°C), keep sealed and dry
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityHygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)0.0
CAS Registry Year (est.)2025

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