Finerenone Impurity 6 CAS 2640280-83-5
| CAS No. | 2640280-83-5 |
| Molecular Formula | C23H28N4O4 |
| Molecular Weight | 424.49 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Finerenone Impurity 6 (CAS 2640280-83-5) is a certified pharmaceutical impurity reference standard with the molecular formula C23H28N4O4 and a molecular weight of 424.49 g/mol.
The molecular framework of Finerenone Impurity 6 (C23H28N4O4) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C23H28N4O4 |
| Molecular Weight | 424.49 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2002 |
| Nitrogen Atoms | 4 |
Related Finerenone Standards
- Finerenone Impurity 73 (CAS CATO-C4X-288073)
- Finerenone Impurity 217 (CAS CATO-C4X-2880217)
- Finerenone Impurity 243 (CAS CATO-C4X-2880243)
- Finerenone Impurity 281 (CAS CATO-C4X-2880281)
- Finerenone Impurity 209 (CAS CATO-C4X-2880209)
- Finerenone Impurity 126 (CAS CATO-C4X-2880126)
- Finerenone Impurity 129 (CAS CATO-C4X-2880129)
- Finerenone impurity 178 (CAS CATO-C4X-2880178)
Recommended Standards
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- Olopatadine Impurity 34 HCl (CAS CATO-C4X-171834)
- Trifarotene Impurity 12 (CAS CATO-C4X-313212)
- Potassium Clavulanate Impurity 21 (CAS CATO-C4X-114621)
- N-(5-Amino-2-methoxyphenyl)-3-methylbenzamide (CAS 926213-69-6)
- 2-(3-Chlorophenoxy)benzaldehyde (CAS 181297-72-3)
- 2-(1-chloroethyl)-5,6-dimethylthieno[2,3-d]pyrimidin-4-amine (CAS 923721-47-5)
- Methyl 2-(methylsulfonyl)-6-oxohexahydropyridazine-4-carboxylate (CAS 339096-89-8)
- (5-bromo-7-methyl-1-benzofuran-2-yl)methanamine (CAS 1343809-80-2)
- (6R,7aS)-6-Hydroxytetrahydro-1H-pyrrolo[1,2-c]imidazole-1,3(2H)-dione (CAS 67943-20-8)
- Semaglutide Impurity 16 (CAS CATO-C4X-222616)
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