Benazepril Impurity B CAS 98626-50-7
| CAS No. | 98626-50-7 |
| Molecular Formula | C24H28N2O5 |
| Molecular Weight | 424.49 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Benazepril Impurity B (CAS 98626-50-7) is a certified pharmaceutical impurity reference standard with the molecular formula C24H28N2O5 and a molecular weight of 424.49 g/mol.
Structurally, Benazepril Impurity B (C24H28N2O5) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 12.0, corresponding to approximately 12 ring(s) or double-bond equivalent(s). With a molecular weight of 424.49 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C24H28N2O5 |
| Molecular Weight | 424.49 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Nitrogen Atoms | 2 |
Related Benazepril Standards
- Benazepril EP Impurity A (CAS 131064-75-0)
- Benazepril EP Impurity B(1R,3S-Isomer) (CAS 86541-76-6)
- Benazepril (CAS 86541-75-5)
- Benazepril-d5 (CAS 1279200-03-1)
- Benazepril EP Impurity D (CAS 112110-48-2)
- Benazepril EP Impurity C (CAS 86541-78-8)
- Benazepril Impurity 13 (CAS CATO-C4X-209613)
- Benazepril tert-Butyl Ester (CAS 109010-61-9)
Recommended Standards
- Ibutilide Impurity 4 (CAS CATO-C4X-21104)
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- Famotidine impurity 64 (CAS CATO-C4X-139264)
- Oclacitinib impurity 8 (CAS CATO-C4X-30188)
- Orforglipron impurity 99 (CAS CATO-C4X-323499)
- Posaconazole Impurity 65 (CAS CATO-C4X-120865)
- 4-Bromo-3-(tert-butyl)-5-cyclopropoxypyridine (CAS 1243286-20-5)
- 4-(Methylthio)benzothioamide (CAS 53550-91-7)
- 1-Bromo-3-isobutoxy-2-methylpropane (CAS 1497146-48-1)
- 2-[(2-Fluoro-4-methylphenyl)amino]pyridine-3-sulfonamide (CAS 1340766-83-7)
- Ethyl 2-(furan-2-yl)-5-methyloxazole-4-carboxylate (CAS 863767-44-6)
- H-Gln-AMC (CAS 105888-45-7)
- D-[Asp]9-Semaglutide (CAS CATO-CPTD788631)
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