1-Acetyl-7-chloro-2,3-dihydroquinolin-4(1H)-one CAS 26413-49-0

Purity 97%+In StockPharmaceutical Standards
CAS No.26413-49-0
Molecular FormulaC11H10ClNO2
Molecular Weight223.66 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

1-Acetyl-7-chloro-2,3-dihydroquinolin-4(1H)-one CAS 26413-49-0 chemical structure

Description

1-Acetyl-7-chloro-2,3-dihydroquinolin-4(1H)-one (CAS 26413-49-0), molecular formula C11H10ClNO2 and molecular weight 223.66 g/mol, is a CATO reference standard with documented purity and traceability.

Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, 1-Acetyl-7-chloro-2,3-dihydroquinolin-4(1H)-one is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 223.66 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 1-Acetyl-7-chloro-2,3-dihydroquinolin-4(1H)-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC11H10ClNO2
Molecular Weight223.66 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)7.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1964
Halogen ContentCl-containing
Nitrogen Atoms1

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