6-(Difluoromethyl)-2-naphthaldehyde CAS 264283-76-3

Purity 97%+In StockPharmaceutical Standards
CAS No.264283-76-3
Molecular FormulaC12H8F2O
Molecular Weight206.19 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

6-(Difluoromethyl)-2-naphthaldehyde CAS 264283-76-3 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 206.19 g/mol gives 6-(Difluoromethyl)-2-naphthaldehyde distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

6-(Difluoromethyl)-2-naphthaldehyde (CAS 264283-76-3), molecular formula C12H8F2O and molecular weight 206.19 g/mol, is a CATO reference standard with documented purity and traceability.

6-(Difluoromethyl)-2-naphthaldehyde (C12H8F2O) contains a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC12H8F2O
Molecular Weight206.19 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)8.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Halogen ContentF-containing

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Why CATO?