4-(3-(3-(Trifluoromethyl)phenyl)isoxazol-5-yl)pyrimidin-2-amine CAS 264616-57-1
| CAS No. | 264616-57-1 |
| Molecular Formula | C14H9F3N4O |
| Molecular Weight | 306.24 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
4-(3-(3-(Trifluoromethyl)phenyl)isoxazol-5-yl)pyrimidin-2-amine (CAS 264616-57-1) is a high-purity analytical reference standard with the molecular formula C14H9F3N4O and a molecular weight of 306.24 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, 4-(3-(3-(Trifluoromethyl)phenyl)isoxazol-5-yl)pyrimidin-2-amine is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 306.24 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C14H9F3N4O |
| Molecular Weight | 306.24 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
Related Trifluoromethyl Standards
- 7-(3-(Trifluoromethyl)phenyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide (CAS 115930-92-2)
- 2-(4-(Trifluoromethyl)phenyl)-2H-[1,3]dioxolo[4,5-f]indazole (CAS 1352305-16-8)
- 3-(3-(2-(Trifluoromethyl)phenyl)-1,2,4-oxadiazol-5-yl)pyridin-2-amine (CAS 1707576-34-8)
- 1-[2-(Trifluoromethyl)phenyl]imidazo[1,5-a]pyridine-3-carboxylic acid (CAS 2059993-43-8)
- 2-((3-(Trifluoromethyl)phenyl)amino)-4H-benzo[d][1,3]oxazin-4-one (CAS 282529-88-8)
- 2-{[4-(trifluoromethyl)phenyl]amino}-4H-3,1-benzoxazin-4-one (CAS 278609-56-6)
- 4-(8-(Trifluoromethyl)imidazo[1,2-a]pyridin-2-yl)benzoic acid (CAS 2197062-06-7)
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Recommended Standards
- 3-Hydroxy-2-(3-(trifluoromethyl)phenyl)quinazolin-4(3H)-one (CAS 306978-91-6)
- 3-(4-Acetylphenoxy)-5-(trifluoromethyl)pyridine-2-carbonitrile (CAS 339278-36-3)
- 7-Hydroxy-3-phenyl-2-(trifluoromethyl)-4h-chromen-4-one (CAS 84858-65-1)
- 2-Cyano-3-(5-(3-(trifluoromethyl)phenyl)furan-2-yl)acrylamide (CAS 301691-25-8)
- 2-Chloro-4-(1-methyl-1h-pyrazol-5-yl)pyrimidine (CAS 1503746-05-1)
- 2-((3-Fluoro-4-methoxyphenyl)amino)pyridine-3-sulfonamide (CAS 1340753-74-3)
- 1-(4-Isopropoxyphenyl)propan-1-one (CAS 35081-48-2)
- N2-Benzyloxycarbonyl-L-homoglutamine (CAS 83793-19-5)
- 4-(Azetidine-1-sulfonyl)phenol (CAS 1394918-86-5)
- 2-Propenoic acid, 2-methyl-, polymer with ethenylbenzene, 2-ethylhexyl 2-propenoate and methyl 2-methyl-2-propenoate (CAS 28377-44-8)
- H-Asp-Gln-OH (CAS 13433-13-1)
- 3-((tert-Butyldimethylsilyl)oxy)propanoic acid (CAS 120821-20-7)
- Iomeprol Impurity 17 (CAS CATO-C4X-182017)
- [Nva12]-Tirzepatide (CAS CATO-C4X-324042)
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