1-[2-(Trifluoromethyl)phenyl]imidazo[1,5-a]pyridine-3-carboxylic acid CAS 2059993-43-8
| CAS No. | 2059993-43-8 |
| Molecular Formula | C15H9F3N2O2 |
| Molecular Weight | 306.24 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 1-[2-(Trifluoromethyl)phenyl]imidazo[1,5-a]pyridine-3-carboxylic acid (CAS 2059993-43-8), a certified reference material (molecular formula C15H9F3N2O2, MW 306.24 g/mol) for analytical method development and quality control.
The molecular framework of 1-[2-(Trifluoromethyl)phenyl]imidazo[1,5-a]pyridine-3-carboxylic acid (C15H9F3N2O2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C15H9F3N2O2 |
| Molecular Weight | 306.24 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1997 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Trifluoromethyl Standards
- 7-(3-(Trifluoromethyl)phenyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide (CAS 115930-92-2)
- 2-(4-(Trifluoromethyl)phenyl)-2H-[1,3]dioxolo[4,5-f]indazole (CAS 1352305-16-8)
- 3-(3-(2-(Trifluoromethyl)phenyl)-1,2,4-oxadiazol-5-yl)pyridin-2-amine (CAS 1707576-34-8)
- 2-((3-(Trifluoromethyl)phenyl)amino)-4H-benzo[d][1,3]oxazin-4-one (CAS 282529-88-8)
- 2-{[4-(trifluoromethyl)phenyl]amino}-4H-3,1-benzoxazin-4-one (CAS 278609-56-6)
- 4-(3-(3-(Trifluoromethyl)phenyl)isoxazol-5-yl)pyrimidin-2-amine (CAS 264616-57-1)
- 4-(8-(Trifluoromethyl)imidazo[1,2-a]pyridin-2-yl)benzoic acid (CAS 2197062-06-7)
- 2-(Trifluoromethyl)-N-(4-(trifluoromethyl)phenyl)pyridin-4-amine (CAS 338401-83-5)
Recommended Standards
- 1,1-Dimethylethyl N-[2-nitro-4-(trifluoromethyl)phenyl]carbamate (CAS 579474-18-3)
- (R)-tert-Butyl 3-(3-bromopropyl)piperidine-1-carboxylate (CAS 193629-36-6)
- 2-(3-(Trifluoromethoxy)phenyl)quinazolin-4(1H)-one (CAS 83800-85-5)
- tert-Butyl 3-(3-bromopropyl)piperidine-1-carboxylate (CAS 193629-30-0)
- (2-Chloro-1,3-thiazol-5-yl)methyl N-(3,4-dichlorophenyl)carbamate (CAS 341967-59-7)
- N,2-Dimethyl-4- pyrimidinamine (CAS 33643-90-2)
- 1-Mesityl-2-methylpropan-2-amine (CAS 92111-19-8)
- N-(3-Fluoro-4-methylphenyl)-2-methoxybenzamide (CAS 903800-72-6)
- 1-Morpholino-2-(3-(phenylsulfonyl)-1H-indol-1-yl)ethan-1-one (CAS 941878-73-5)
- 2-Amino-2-(4-chloro-3-nitrophenyl)acetic Acid (CAS 768347-03-1)
- 2-(Adamantan-1-yl)aniline (CAS 143571-14-6)
- 8-(Azetidin-3-yloxy)-2-methylquinoline dihydrochloride (CAS 1864060-43-4)
- Morpholino(5-(pyridin-3-ylmethyl)-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridin-3-yl)methanone (CAS 1775435-26-1)
- Peptide 46 (H-4054.0500) (CAS 192122-40-0)
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