5-Amino-1-(2-chloro-5-(trifluoromethyl)phenyl)-3-methyl-1H-pyrazole-4-carbothioamide CAS 265314-27-0
| CAS No. | 265314-27-0 |
| Molecular Formula | C12H10ClF3N4S |
| Molecular Weight | 334.75 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 334.75 g/mol gives 5-Amino-1-(2-chloro-5-(trifluoromethyl)phenyl)-3-methyl-1H-pyrazole-4-carbothioamide distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
5-Amino-1-(2-chloro-5-(trifluoromethyl)phenyl)-3-methyl-1H-pyrazole-4-carbothioamide (CAS 265314-27-0), molecular formula C12H10ClF3N4S and molecular weight 334.75 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 5-Amino-1-(2-chloro-5-(trifluoromethyl)phenyl)-3-methyl-1H-pyrazole-4-carbothioamide (C12H10ClF3N4S) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 8.0, corresponding to approximately 8 ring(s) or double-bond equivalent(s). With a molecular weight of 334.75 g/mol, it falls into the moderately-high-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H10ClF3N4S |
| Molecular Weight | 334.75 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related Amino Standards
- Methyl 2-{2-amino-2-[2-(6-chloro-2-pyridinyl)hydrazono]ethoxy}benzenecarboxylate (CAS 338756-17-5)
- 4-Amino-N-(4-chlorophthalazin-1-yl)benzenesulfonamide (CAS 16352-00-4)
- N-(5-Amino-2-methoxyphenyl)-2-(4-chloro-3,5-dimethylphenoxy)acetamide (CAS 1020054-26-5)
- N-(3-Amino-4-chlorophenyl)-4-(2-ethoxyethoxy)-benzamide (CAS 1020054-56-1)
- N-(3-Amino-4-chlorophenyl)-2-(2-ethoxyethoxy)-benzamide (CAS 1020054-59-4)
- N-(3-Amino-4-chlorophenyl)-3-(2-ethoxyethoxy)-benzamide (CAS 1020054-65-2)
- 2-Amino-5-(3-((4-(2-chloroacetyl)phenyl)amino)propyl)-6-methylpyrimidin-4(3H)-one (CAS 2499-51-6)
- N-(4-amino-2,5-diethoxyphenyl)-2-chlorobenzamide (CAS 483321-56-8)
Recommended Standards
- 4-(4-chloro-3-nitrophenyl)-2-(4-fluorophenyl)-1,3-thiazole (CAS 260788-64-5)
- Ethyl 2-(5-chloro-2-oxo-3-(phenylcarbamoyl)pyridin-1(2H)-yl)acetate (CAS 339028-37-4)
- 4-(1-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)thio)ethyl)pyrimidin-2-amine (CAS 338397-88-9)
- Methyl 4-(3-(4-chlorophenyl)ureido)-2-methoxybenzoate (CAS 477889-66-0)
- 2-(4-(Tributylstannyl)thiazol-2-yl)propan-2-ol (CAS 1245816-16-3)
- 4-Trifluoromethoxy-2-biphenyl)boronic acid (CAS 2121514-20-1)
- 5-Ethoxy-6-methyl-3-phenyl-1,2,4-triazine (CAS 116177-94-7)
- 2H-1-Benzopyran-2-one, 5-methoxy-4-methyl- (CAS 30924-62-0)
- 1-Methyl-2-oxo-1,2,3,4-tetrahydroquinoline-6-sulfonyl chloride (CAS 140618-96-8)
- 3,5-Dibromo-4-fluorocinnamic acid (CAS 1807312-50-0)
- 1-Cyclopropylpiperidin-4-amine dihydrochloride (CAS 1176419-75-2)
- tert-Butyl 4-(2-chloro-5-fluoropyrimidin-4-yl)piperidine-1-carboxylate (CAS 1053657-03-6)
- (S)-2-Amino-5-hydroxypentanoic Acid (CAS 6152-89-2)
- Staphylococcus Aureus Protein A (SpA)-Derived Peptide (H-2228.0005) (CAS 144979-26-0)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com