4-(1-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)thio)ethyl)pyrimidin-2-amine CAS 338397-88-9
| CAS No. | 338397-88-9 |
| Molecular Formula | C12H10ClF3N4S |
| Molecular Weight | 334.75 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4-(1-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)thio)ethyl)pyrimidin-2-amine (C12H10ClF3N4S) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
4-(1-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)thio)ethyl)pyrimidin-2-amine (CAS 338397-88-9), molecular formula C12H10ClF3N4S and molecular weight 334.75 g/mol, is a CATO reference standard with documented purity and traceability.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 4-(1-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)thio)ethyl)pyrimidin-2-amine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H10ClF3N4S |
| Molecular Weight | 334.75 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related Chloro Standards
- 11-Chloro-2,4-dimethyl-4,6a,7,12b-tetrahydro-1H,6H-chromeno[4',3':4,5]pyrano[2,3-d]pyrimidine-1,3(2H)-dione (CAS 338954-18-0)
- 2-Chloro-6-ethoxy-4-formylphenyl 4-methoxybenzoate (CAS 444079-67-8)
- 3-((4-Chloro-3-nitrophenyl)amino)-1-(4-methoxyphenyl)propan-1-one (CAS 882748-62-1)
- 3-((5-Chloro-2-methoxyphenyl)amino)-1-(4-nitrophenyl)propan-1-one (CAS 939888-40-1)
- 3-[(2-Chloro-6-ethoxy-4-formylphenoxy)methyl]benzoic acid (CAS 428843-08-7)
- 4-(4-chloro-3-nitrophenyl)-2-(4-fluorophenyl)-1,3-thiazole (CAS 260788-64-5)
- Ethyl 2-(5-chloro-2-oxo-3-(phenylcarbamoyl)pyridin-1(2H)-yl)acetate (CAS 339028-37-4)
- (E)-2-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-2-(thiophen-2-yl)acetaldehyde O-methyl oxime (CAS 338770-60-8)
Recommended Standards
- 5-Amino-1-(2-chloro-5-(trifluoromethyl)phenyl)-3-methyl-1H-pyrazole-4-carbothioamide (CAS 265314-27-0)
- Methyl 4-(3-(4-chlorophenyl)ureido)-2-methoxybenzoate (CAS 477889-66-0)
- Fenoldopam Impurity 1 (CAS CATO-C4X-29811)
- n-[4-(chloromethyl)-1,3-thiazol-2-yl]-n-[3-(trifluoromethyl)phenyl]acetamide (CAS 757222-04-1)
- 4-(4-(tert-Butyl)benzyl)piperidine (CAS 112937-99-2)
- 1-Chloro-3,5-Bis-(4-chlorobenzoyl)-2-deoxy-D-ribofuranose (CAS 21740-23-8)
- 5-(Bromomethyl)-3-(4-chlorophenyl)-1,2,4-oxadiazole (CAS 721428-29-1)
- 1-(4-Fluorobenzyl)-4-(hydroxymethyl)pyrrolidin-2-one (CAS 96449-66-0)
- 8-Acetonyldihydronitidine (CAS 80330-39-8)
- 3-Methoxypropane-1-sulfonyl chloride (CAS 64297-55-8)
- 2,5-Diazabicyclo[2.2.1]heptane-2-carboxylic acid, 6-(trifluoromethyl)-, 1,1-dimethylethyl ester (CAS 1250995-58-4)
- N-Allyl-4-chlorobenzamide (CAS 5866-99-9)
- 2-Hexylquinolin-4(1H)-one (CAS 18813-68-8)
- Nonapeptide-1 (CAS 158563-45-2)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com