Memantine impurity 53 CAS 26562-81-2
| CAS No. | 26562-81-2 |
| Molecular Formula | C10H18N2 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Memantine impurity 53.
As a process- or degradation-related impurity, Memantine impurity 53 (CAS 26562-81-2, C10H18N2HCl) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Memantine impurity 53 (C10H18N2HCl) is characterized by a nitrile group, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Memantine impurity 53 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H18N2 2*HCl |
| Molecular Weight | 202.73 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1964 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Memantine Standards
- Memantine Impurity 61 (CAS 111035-07-5)
- Memantine Lactose Adduct (CAS 1159637-28-1)
- Memantine-d6 Hydrochloride (CAS 1189713-18-5)
- Memantine Related Compound 3 (CAS 1262583-10-7)
- Memantine-d3 HCl (CAS 1329802-06-3)
- Memantine Glycine (CAS 1340545-88-1)
- Memantine Impurity 62 (CAS 14931-70-5)
- Memantine Related Compound H (CAS 15210-60-3)
Recommended Standards
- Vortioxetine Impurity 95 (CAS 1446750-99-7（free base）)
- Phenylephrine Impurity 86 (CAS CATO-C4X-146786)
- Ibrutinib Impurity 65 (CAS CATO-C4X-106465)
- 6-Chloro-1-indanone (CAS 14548-38-0)
- 5-Morpholinopyridin-2-amine, 97% (CAS 571189-78-1)
- Cholesterol-26,26,26,27,27,27-d6 (CAS 60816-17-3)
- 2-(4-Chlorophenyl)-2-phenylacetic acid (CAS 21771-88-0)
- 4-Fluoro-N-(2-(imidazo[1,2-a]pyridin-2-yl)ethyl)benzenesulfonamide (CAS 868978-56-7)
- (S)-(+)-2-(tert-Butyl)-3-methyl-4-imidazolidinone trifluoroacetic acid (S)-(+)-2-(tert-Butyl)-3-methyl-4-oxoimidazolidinium trifluoroacetate (S)-2-(tert-Butyl)-3-methyl-4-imidazolidinone trifluoroacetic acid salt 900503-70-0 (CAS 900503-70-0)
- Myristoyl Pentapeptide-4 (CAS 1392416-25-9)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com