5-(chloromethyl)-1-ethyl-1H-1,2,4-triazole hydrochloride CAS 265644-02-8
| CAS No. | 265644-02-8 |
| Molecular Formula | C5H8ClN3 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
5-(chloromethyl)-1-ethyl-1H-1,2,4-triazole hydrochloride (CAS 265644-02-8), molecular formula C5H8ClN3HCl and molecular weight 182.05 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 5-(chloromethyl)-1-ethyl-1H-1,2,4-triazole hydrochloride (C5H8ClN3HCl) is characterized by a nitrile group, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C5H8ClN3 HCl |
| Molecular Weight | 182.05 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related chloromethyl Standards
- 7-(Chloromethyl)-3-methyl-5H-thiazolo[3,2-a]pyrimidin-5-one (CAS 100003-81-4)
- 7-(Chloromethyl)-2,3-dimethyl-5H-thiazolo[3,2-a]pyrimidin-5-one (CAS 100003-82-5)
- 7-(Chloromethyl)-3-(4-chlorophenyl)-5H-thiazolo[3,2-a]pyrimidin-5-one (CAS 100003-85-8)
- chloromethyl 2-ethoxy-2-methylpropanoate (CAS 1000296-74-1)
- 5-(chloromethyl)-N-(4-methylbenzyl)-1,3,4-thiadiazole-2-carboxamide (CAS 1000932-24-0)
- 5-(Chloromethyl)-7-ethoxy-2-(trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyrimidine (CAS 1000932-47-7)
- 5-(chloromethyl)-N-(4-fluorobenzyl)-1,3,4-thiadiazole-2-carboxamide (CAS 1000932-60-4)
- 2-(Chloromethyl)-5,6-diphenylfuro[2,3-d]pyrimidin-4-amine (CAS 1000933-67-4)
Recommended Standards
- 9,10-Dichlorostearic Acid (CAS 5829-48-1)
- 5,6,7,8-Tetrahydroquinoxaline-2-carboxylic acid (CAS 742070-41-3)
- (2-Butoxy-5-fluorophenyl)boronic Acid (CAS 480438-62-8)
- Spiro[cyclobutane-1,2'-thiochroman]-4'-one 1',1'-dioxide (CAS 934555-21-2)
- 3-(1-TRITYL-1H-IMIDAZOL-4-YL)PROPAN-1-OL (CAS 152030-49-4)
- 2-(4-bromo-2-formylphenoxy)acetamide (CAS 515832-69-6)
- 1-(2-(Isopropyl(methyl)amino)ethyl)cyclobutan-1-amine (CAS 1534123-88-0)
- Tert-butyl (R)-2-(chloromethyl)morpholine-4-carboxylate (CAS 1260589-87-4)
- N-Methylbutyramide (CAS 17794-44-4)
- Stresscopin-Related Peptide (human) (CAS 348626-74-4)
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