Spiro[cyclobutane-1,2'-thiochroman]-4'-one 1',1'-dioxide CAS 934555-21-2
| CAS No. | 934555-21-2 |
| Molecular Formula | C12H18O3S |
| Molecular Weight | 242.33 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Spiro[cyclobutane-1,2'-thiochroman]-4'-one 1',1'-dioxide (CAS 934555-21-2) is a high-purity analytical reference standard with the molecular formula C12H18O3S and a molecular weight of 242.33 g/mol.
The molecular framework of Spiro[cyclobutane-1,2'-thiochroman]-4'-one 1',1'-dioxide (C12H18O3S) is characterized by a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), Spiro[cyclobutane-1,2'-thiochroman]-4'-one 1',1'-dioxide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H18O3S |
| Molecular Weight | 242.33 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Sulfur Atoms | 1 |
Related Spiro Standards
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- Methyl spiro[cyclohexane-1,3'-indoline]-4-carboxylate (CAS 268538-23-4)
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Recommended Standards
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- n-Pentyl Toluenesulfonate (CAS 4450-76-4)
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- 2-[(4-Chlorophenyl)methyl]-N-(3,5-dichlorophenyl)-1,3-thiazole-4-carboxamide (CAS 478030-43-2)
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