2,2-difluoro-2-(pyridin-2-yl)ethan-1-ol CAS 267875-65-0
| CAS No. | 267875-65-0 |
| Molecular Formula | C7H13F2NO |
| Molecular Weight | 165.18 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
2,2-difluoro-2-(pyridin-2-yl)ethan-1-ol (CAS 267875-65-0) is a high-purity analytical reference standard with the molecular formula C7H13F2NO and a molecular weight of 165.18 g/mol.
The molecular framework of 2,2-difluoro-2-(pyridin-2-yl)ethan-1-ol (C7H13F2NO) is characterized by an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
As a certified reference material (CRM), 2,2-difluoro-2-(pyridin-2-yl)ethan-1-ol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H13F2NO |
| Molecular Weight | 165.18 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 1.0 |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related difluoro Standards
- 2,2-Difluoro-2-(tetrahydro-2H-pyran-4-yl)ethan-1-amine (CAS 1048963-32-1)
- 2,2-Difluoro-N-((tetrahydrofuran-2-yl)methyl)ethan-1-amine (CAS 1182935-72-3)
- (4,4-Difluoro-1,2-dimethylpyrrolidin-2-yl)methanol (CAS 2417920-29-5)
- (4,4-Difluoro-5-methylpiperidin-3-yl)methanol (CAS 2366182-30-9)
- (5,5-Difluoro-1-methylpiperidin-3-yl)methanol (CAS 2757097-14-4)
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- 2,2-Difluoro-1-(1,3-thiazol-2-yl)ethan-1-ol (CAS 1312535-16-2)
Recommended Standards
- 2-(difluoromethyl)-2,6-dimethylmorpholine (CAS 2031260-50-9)
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- 2-(4,4-Difluoropiperidin-1-yl)ethan-1-ol (CAS 276862-11-4)
- 4-(Difluoromethoxy)-2-methylpiperidine (CAS 2306261-80-1)
- 4-methylphthalazin-1-amine (CAS 4776-85-6)
- (1-methyl-2-oxabicyclo[2.1.1]hexan-4-yl)methanol (CAS 2138162-49-7)
- 2-Chloro-5-cyanobenzoyl chloride (CAS 122483-59-4)
- 2-Methoxy-6-(pyrrolidin-1-yl)pyridine (CAS 380500-10-7)
- 4-(2-(4-Methoxyphenyl)quinolin-4-yl)morpholine (CAS 853331-20-1)
- 3-Bromopyridine-2-carboximidamide;hydrochloride (CAS 1179360-60-1)
- 2-chloro-5-methoxy-pyridin-4-ol (CAS 1196145-74-0)
- tert-Butyl (5-methylisoxazol-3-yl)carbamate (CAS 97517-66-3)
- 1N-Hydroxyl-6-bromo-5-azaindole (CAS 1000342-28-8)
- Peptide Impurity 82 (CAS 10491-78-8)
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