Thioctic acid impurity 61 CAS 26825-92-3

Purity 97%+In StockPharmacopoeial Impurity Standards
CAS No.26825-92-3
Molecular FormulaC9H17BrO2
Molecular Weight237.13 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Thioctic acid impurity 61 CAS 26825-92-3 chemical structure

Description

Thioctic acid impurity 61 (CAS 26825-92-3) is a certified pharmaceutical impurity reference standard with the molecular formula C9H17BrO2 and a molecular weight of 237.13 g/mol.

The molecular framework of Thioctic acid impurity 61 (C9H17BrO2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC9H17BrO2
Molecular Weight237.13 g/mol
Purity97%+
StorageStore at room temperature, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityContains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)1.0
CAS Registry Year (est.)1964
Halogen ContentBr-containing

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