Ivacaftor impurity 19 CAS CATO-C4X-296419
| CAS No. | CATO-C4X-296419 |
| Molecular Formula | C24H27N3O4 |
| Molecular Weight | 421.49 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Ivacaftor impurity 19 (CAS CATO-C4X-296419) is a certified pharmaceutical impurity reference standard with the molecular formula C24H27N3O4 and a molecular weight of 421.49 g/mol.
Based on its molecular formula C24H27N3O4, Ivacaftor impurity 19 contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 421.49 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C24H27N3O4 |
| Molecular Weight | 421.49 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 3 |
Related Ivacaftor Standards
- Ivacaftor impurity 16 (CAS CATO-C4X-296416)
- Ivacaftor Impurity 20 (CAS CATO-C4X-296420)
- Ivacaftor Carboxylic Acid (CAS 1246213-24-0)
- Ivacaftor Carboxylic Acid Lactone (CAS 1246213-41-1)
- Ivacaftor-d9 (CAS 1413431-07-8)
- Ivacaftor-d4 (CAS CATO-C4X-296421)
- Ivacaftor-d18 (CAS 1413431-05-6)
- Ivacaftor Impurity 15 (CAS 2760759-58-6)
Recommended Standards
- Finerenone Impurity 209 (CAS CATO-C4X-2880209)
- (E)-Fenpyroximate (CAS 134098-61-6)
- Daprodustat impurity 27 (CAS 960540-96-9)
- Fenpyroximate (CAS 111812-58-9)
- Metoprolol Impurity 2 (Mixture of Z and E Isomers) (CAS 82961-02-2)
- Dapagliflozin Impurity 148 (CAS 342043-51-0)
- Fluticasone Impurity 100 (CAS 2408725-66-4)
- Febuxostat Impurity 78 (CAS CATO-C4X-116278)
- 2-Amino-5-chloronicotinaldehyde (CAS 54856-61-0)
- 3-Cyclopropoxy-2,4-diisopropoxypyridine (CAS 1243463-27-5)
- Methyl 4-(3-piperidinyloxy)benzoate hydrochloride (CAS 1220019-94-2)
- 3,5-Dichloro-N-methylaniline (CAS 42266-03-5)
- 4-((2-Methoxybenzyl)oxy)piperidine (CAS 86928-12-3)
- Insulin Degludec Impurity 18 (CAS CATO-C4X-215718)
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