Linezolid Impurity 12 CAS 2689-39-6
| CAS No. | 2689-39-6 |
| Molecular Formula | C10H11FN2O3 |
| Molecular Weight | 226.20 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Linezolid Impurity 12 (CAS 2689-39-6) is a certified pharmaceutical impurity reference standard with the molecular formula C10H11FN2O3 and a molecular weight of 226.20 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, Linezolid Impurity 12 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 226.20 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Linezolid Impurity 12 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H11FN2O3 |
| Molecular Weight | 226.20 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Linezolid Standards
- Linezolid Impurity 87 (CAS 238418-75-2)
- Linezolid Impurity 88 (CAS 1233955-40-2)
- Linezolid Impurity 35 (CAS 1345879-87-9)
- Linezolid Impurity 51 (CAS 1807854-53-0)
- Linezolid Impurity 111 (CAS 588708-63-8)
- Linezolid Impurity 36 (CAS 3459-92-5)
- Linezolid Impurity 69 (CAS 10389-51-2)
- Linezolid Impurity 80 (CAS 70887-96-6)
Recommended Standards
- Celecoxib Impurity 54 (CAS 948293-46-7)
- Celecoxib Impurity 11 (CAS 219986-64-8)
- 4-(Trifluoromethoxy)benzamidoxime n-hydroxy-4-trifluoromethoxy-benzamidine n'-hydroxy-4-(trifluoromethoxy)benzene carboximidamide n'-hydroxy-4-(trifluoromethoxy)benzenecarboximidamide n'-hydroxy-4-(trifluoromethoxy)benzene-1-carboximidamide 56935-71-8 (CAS 56935-71-8)
- 2-((2-Nitrophenyl)sulfonyl)acetonitrile (CAS 100559-85-1)
- Exemestane EP Impurity I (CAS CATO-C4X-164122)
- Morantel Impurity 2 (CAS 2680539-26-6(free base))
- Niraparib Impurity 66 (CAS CATO-C4X-232966)
- 2-(3-Carbamoyl-4-iodo-1H-pyrazol-1-yl)acetic acid (CAS 1354706-04-9)
- 2,4-Diethylthiophen-3-amine hydrochloride (CAS 2567556-39-0)
- 3-Hydroxy-4-((3-hydroxypropyl)amino)tetrahydrothiophene 1,1-dioxide (CAS 459413-88-8)
- N-(5-(2-Chlorophenyl)-1,3,4-oxadiazol-2-yl)-2-(phenylthio)acetamide (CAS 895487-48-6)
- 1-(3,4-Dihydroisoquinolin-2(1H)-yl)propan-2-amine (CAS 54151-52-9)
- 2-Methoxynaphthalene-6-d (CAS 68251-84-3)
- (Leu31,Pro3?)-Neuropeptide Y (human, rat) trifluoroacetate salt (CAS 132699-73-1)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com