Celecoxib Impurity 11 CAS 219986-64-8
| CAS No. | 219986-64-8 |
| Molecular Formula | C11H9F3N2 |
| Molecular Weight | 226.20 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Celecoxib Impurity 11 (CAS 219986-64-8) is a certified pharmaceutical impurity reference standard with the molecular formula C11H9F3N2 and a molecular weight of 226.20 g/mol.
Structurally, Celecoxib Impurity 11 (C11H9F3N2) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 7.0, corresponding to approximately 7 ring(s) or double-bond equivalent(s). With a molecular weight of 226.20 g/mol, it falls into the medium-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
As a certified reference material (CRM), Celecoxib Impurity 11 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H9F3N2 |
| Molecular Weight | 226.20 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2019 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Celecoxib Standards
- Celecoxib Impurity 54 (CAS 948293-46-7)
- Celecoxib Impurity 1 (CAS 54779-81-6)
- Celecoxib Impurity 22 (CAS 163266-02-2)
- Celecoxib Impurity 25 (CAS CATO-C4X-104325)
- Celecoxib Impurity 49 (CAS 720-94-5)
- Celecoxib Impurity 67 (CAS 910303-54-7)
- Celecoxib Impurity 57 (CAS CATO-C4X-104357)
- Celecoxib Impurity 59 (CAS CATO-C4X-104359)
Recommended Standards
- 4-(Trifluoromethoxy)benzamidoxime n-hydroxy-4-trifluoromethoxy-benzamidine n'-hydroxy-4-(trifluoromethoxy)benzene carboximidamide n'-hydroxy-4-(trifluoromethoxy)benzenecarboximidamide n'-hydroxy-4-(trifluoromethoxy)benzene-1-carboximidamide 56935-71-8 (CAS 56935-71-8)
- N1-(4-Fluorophenyl)-N2-(2-hydroxyethyl)oxalamide (CAS 357268-60-1)
- Linezolid Impurity 12 (CAS 2689-39-6)
- Methyl 5-fluoro-2-(2-methoxy-2-oxoethyl)benzoate (CAS 2326068-11-3)
- Cefmenoxime Impurity 10 (CAS CATO-C4X-147710)
- Silodosin Impurity 15 (CAS 2052161-50-7)
- Amorolfine Impurity 31 (CAS CATO-C4X-154231)
- 8-Bromo-6-(trifluoromethoxy)-1,2,3,4-tetrahydroquinoline (CAS 2366994-29-6)
- 1-(4-Bromo-2-fluorophenyl)cyclopropan-1-ol (CAS 1250254-02-4)
- (7-Amino-1-methyl-1H-indol-3-yl)methanol (CAS 1895523-88-2)
- 2-((9,10-Dioxo-9,10-dihydroanthracen-1-yl)amino)benzoic acid (CAS 19795-96-1)
- 6-Ethylquinoline (CAS 19655-60-8)
- 1-(3,5-Dimethyl-1H-pyrrol-2-yl)-1,3-butanedione (CAS 22511-75-7)
- Pheromone Biosynthesis Activating Neuropeptide (Helicoverpa assulta, Heliothis zea) (CAS 122071-54-9)
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