Busulfan Impurity 18 CAS 343928-18-7

Purity >90%In StockPharmacopoeial Impurity Standards
CAS No.343928-18-7
Molecular FormulaC5H12O4S
Molecular Weight168.21 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Busulfan Impurity 18 CAS 343928-18-7 chemical structure

Description

As a process- or degradation-related impurity, Busulfan Impurity 18 (CAS 343928-18-7, C5H12O4S) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.

The molecular framework of Busulfan Impurity 18 (C5H12O4S) is characterized by a carbohydrate-derived structure, a sulfone group. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development.

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

CATO manufactures Busulfan Impurity 18 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC5H12O4S
Molecular Weight168.21 g/mol
Purity>90%
StorageStore at 2-8°C, keep sealed and dry
Solubility (reference)Soluble in methanol, ethanol, DMSO, water
StabilityHygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)0.0
CAS Registry Year (est.)2025
Sulfur Atoms1

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