Fmoc-(R)-3-amino-4-(2-cyano-phenyl)-butyric acid CAS 269726-81-0

Purity 97%+In StockPharmaceutical Standards
CAS No.269726-81-0
Molecular FormulaC26H22N2O4
Molecular Weight426.46 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

Fmoc-(R)-3-amino-4-(2-cyano-phenyl)-butyric acid CAS 269726-81-0 chemical structure

Description

The occurrence of Fmoc-(R)-3-amino-4-(2-cyano-phenyl)-butyric acid is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

Fmoc-(R)-3-amino-4-(2-cyano-phenyl)-butyric acid (CAS 269726-81-0) is a high-purity analytical reference standard with the molecular formula C26H22N2O4 and a molecular weight of 426.46 g/mol.

The molecular framework of Fmoc-(R)-3-amino-4-(2-cyano-phenyl)-butyric acid (C26H22N2O4) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), Fmoc-(R)-3-amino-4-(2-cyano-phenyl)-butyric acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC26H22N2O4
Molecular Weight426.46 g/mol
AppearancePale yellow to yellow crystalline powder
Purity97%+
StorageStore in a cool place (≤25°C), protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)17.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Nitrogen Atoms2

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