Cefathiamidine Impurity 2 CAS 26973-80-8

Purity 97%+In StockPharmacopoeial Impurity Standards
CAS No.26973-80-8
Molecular FormulaC12H13BrN2O6S
Molecular Weight393.21 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Cefathiamidine Impurity 2 CAS 26973-80-8 chemical structure

Description

This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.

CATO supplies Cefathiamidine Impurity 2 (CAS 26973-80-8), a pharmacopoeial impurity reference standard (molecular formula C12H13BrN2O6S, MW 393.21 g/mol) used for the identification and quantification of trace impurities in APIs.

The molecular framework of Cefathiamidine Impurity 2 (C12H13BrN2O6S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

CATO manufactures Cefathiamidine Impurity 2 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC12H13BrN2O6S
Molecular Weight393.21 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)7.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1964
Halogen ContentBr-containing
Nitrogen Atoms2
Sulfur Atoms1

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