Metaraminol Impurity 58 CAS 26988-39-6
| CAS No. | 26988-39-6 |
| Molecular Formula | C26H22O2 |
| Molecular Weight | 366.45 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Metaraminol Impurity 58.
As a process- or degradation-related impurity, Metaraminol Impurity 58 (CAS 26988-39-6, C26H22O2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Metaraminol Impurity 58 (C26H22O2) is characterized by a steroid core, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Metaraminol Impurity 58 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C26H22O2 |
| Molecular Weight | 366.45 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1964 |
Related Metaraminol Standards
- Metaraminol Impurity 100 (CAS CATO-C4X-2252100)
- Metaraminol Impurity 113 (CAS CATO-C4X-2252113)
- Metaraminol Impurity 114 (CAS CATO-C4X-2252114)
- Metaraminol Impurity 23 (CAS 2151127-61-4)
- Metaraminol Impurity 106 (CAS CATO-C4X-2252106)
- Metaraminol Impurity 109 (CAS CATO-C4X-2252109)
- Metaraminol Impurity 33 (CAS CATO-C4X-225233)
- Metaraminol Impurity 95 (CAS CATO-C4X-225295)
Recommended Standards
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- Erbon (CAS 136-25-4)
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- Finerenone Impurity 116 (CAS CATO-C4X-2880116)
- Acarbose EP Impurity F (CAS CATO-C4X-11736)
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- H-D-Met-Met-Met-OH (H-4365.0250) (CAS 319927-24-7)
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- 6-Isocyanato-2,2,4,4-tetrafluoro-1,3-benzodioxane (CAS 26030-46-6)
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